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TMEM212 transmembrane protein 212 [ Homo sapiens (human) ]

Gene ID: 389177, updated on 10-Oct-2023

Summary

Official Symbol
TMEM212provided by HGNC
Official Full Name
transmembrane protein 212provided by HGNC
Primary source
HGNC:HGNC:34295
See related
Ensembl:ENSG00000186329 AllianceGenome:HGNC:34295
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See TMEM212 in Genome Data Viewer
Location:
3q26.31
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (171843349..171859318)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (174627486..174643481)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (171561139..171577108)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12788 Neighboring gene MT-CO1 pseudogene 58 Neighboring gene phospholipase D1 Neighboring gene small nucleolar RNA U13 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:171436449-171437034 Neighboring gene Sharpr-MPRA regulatory region 14633 Neighboring gene TMEM212 antisense RNA 1 Neighboring gene uncharacterized LOC105374218 Neighboring gene Sharpr-MPRA regulatory region 13471 Neighboring gene uncharacterized LOC105374217 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:171678336-171678836 Neighboring gene FOXA motif-containing MPRA enhancer 130

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
EBI GWAS Catalog
Genome-wide association of BMI in African Americans.
EBI GWAS Catalog
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164436.2NP_001157908.1  transmembrane protein 212

    See identical proteins and their annotated locations for NP_001157908.1

    Status: VALIDATED

    Source sequence(s)
    AK026825, DB199311
    Consensus CDS
    CCDS46958.1
    UniProtKB/Swiss-Prot
    A6NML5
    UniProtKB/TrEMBL
    H7C390
    Related
    ENSP00000334072.5, ENST00000334567.9

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    171843349..171859318
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512817.1XP_011511119.1  transmembrane protein 212 isoform X1

    See identical proteins and their annotated locations for XP_011511119.1

    UniProtKB/Swiss-Prot
    A6NML5
    UniProtKB/TrEMBL
    H7C390
    Related
    ENSP00000484106.1, ENST00000619900.4
  2. XM_017006376.2XP_016861865.1  transmembrane protein 212 isoform X2

    UniProtKB/TrEMBL
    H7C390

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    174627486..174643481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054346480.1XP_054202455.1  transmembrane protein 212 isoform X1

    UniProtKB/Swiss-Prot
    A6NML5
    UniProtKB/TrEMBL
    H7C390
  2. XM_054346481.1XP_054202456.1  transmembrane protein 212 isoform X2

    UniProtKB/TrEMBL
    H7C390