Format

Send to:

Choose Destination

INKA1 inka box actin regulator 1 [ Homo sapiens (human) ]

Gene ID: 389119, updated on 23-Nov-2021

Summary

Official Symbol
INKA1provided by HGNC
Official Full Name
inka box actin regulator 1provided by HGNC
Primary source
HGNC:HGNC:32480
See related
Ensembl:ENSG00000185614
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C3orf54; FAM212A
Expression
Broad expression in skin (RPKM 6.6), lung (RPKM 3.2) and 23 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See INKA1 in Genome Data Viewer
Location:
3p21.31
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49803261..49805030)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (49840694..49842463)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene inositol hexakisphosphate kinase 1 Neighboring gene PHD finger protein 5E pseudogene Neighboring gene cadherin related family member 4 Neighboring gene Sharpr-MPRA regulatory region 10954 Neighboring gene microRNA 5193 Neighboring gene ubiquitin like modifier activating enzyme 7 Neighboring gene TRAF interacting protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC20416

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein serine/threonine kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein serine/threonine kinase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
PAK4-inhibitor INKA1
Names
HInca
Induced in Neural Crest by AP-2alpha
family with sequence similarity 212 member A
induced in neural crest by AP2-alpha protein homolog
protein FAM212A

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366281.1NP_001353210.1  PAK4-inhibitor INKA1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC139451
    Conserved Domains (1) summary
    pfam15342
    Location:138177
    FAM212; FAM212 family
  2. NM_203370.2NP_976248.2  PAK4-inhibitor INKA1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    BC012170
    Consensus CDS
    CCDS2804.1
    Related
    ENSP00000329735.5, ENST00000333323.6
    Conserved Domains (1) summary
    pfam15342
    Location:165204
    FAM212; FAM212 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49803261..49805030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center