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CDHR4 cadherin related family member 4 [ Homo sapiens (human) ]

Gene ID: 389118, updated on 23-Nov-2021

Summary

Official Symbol
CDHR4provided by HGNC
Official Full Name
cadherin related family member 4provided by HGNC
Primary source
HGNC:HGNC:34527
See related
Ensembl:ENSG00000187492
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CDH29; PRO34300
Expression
Biased expression in lung (RPKM 3.2), testis (RPKM 2.4) and 2 other tissues See more
Orthologs
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Genomic context

See CDHR4 in Genome Data Viewer
Location:
3p21.31
Exon count:
24
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49790732..49802741, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (49828165..49837306, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene inositol hexakisphosphate kinase 1 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 14 Neighboring gene PHD finger protein 5E pseudogene Neighboring gene Sharpr-MPRA regulatory region 10954 Neighboring gene inka box actin regulator 1 Neighboring gene microRNA 5193 Neighboring gene ubiquitin like modifier activating enzyme 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC164982

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cadherin-related family member 4
Names
Cadherin-like protein UNQ9392/PRO34300
VLLR9392
cadherin-like 29
cadherin-like protein 29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007540.4NP_001007541.2  cadherin-related family member 4 precursor

    See identical proteins and their annotated locations for NP_001007541.2

    Status: VALIDATED

    Source sequence(s)
    AC139451, AY358221, BC146674, DR008129
    Consensus CDS
    CCDS46829.1
    UniProtKB/Swiss-Prot
    A6H8M9
    Related
    ENSP00000391409.2, ENST00000412678.7
    Conserved Domains (1) summary
    cd11304
    Location:447546
    Cadherin_repeat; Cadherin tandem repeat domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49790732..49802741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011533701.2XP_011532003.1  cadherin-related family member 4 isoform X4

    See identical proteins and their annotated locations for XP_011532003.1

    Conserved Domains (1) summary
    cd11304
    Location:447546
    Cadherin_repeat; Cadherin tandem repeat domain
  2. XM_017006367.1XP_016861856.1  cadherin-related family member 4 isoform X1

    Conserved Domains (1) summary
    cd11304
    Location:499598
    Cadherin_repeat; Cadherin tandem repeat domain
  3. XM_017006369.1XP_016861858.1  cadherin-related family member 4 isoform X3

    Conserved Domains (1) summary
    cd11304
    Location:494593
    Cadherin_repeat; Cadherin tandem repeat domain
  4. XM_017006368.1XP_016861857.1  cadherin-related family member 4 isoform X2

    Conserved Domains (1) summary
    cd11304
    Location:499598
    Cadherin_repeat; Cadherin tandem repeat domain
  5. XM_017006366.1XP_016861855.1  cadherin-related family member 4 isoform X1

    Conserved Domains (1) summary
    cd11304
    Location:499598
    Cadherin_repeat; Cadherin tandem repeat domain
  6. XM_011533700.3XP_011532002.1  cadherin-related family member 4 isoform X4

    See identical proteins and their annotated locations for XP_011532002.1

    Conserved Domains (1) summary
    cd11304
    Location:447546
    Cadherin_repeat; Cadherin tandem repeat domain
  7. XM_017006370.1XP_016861859.1  cadherin-related family member 4 isoform X5

  8. XM_017006371.1XP_016861860.1  cadherin-related family member 4 isoform X5

RNA

  1. XR_001740142.1 RNA Sequence

  2. XR_001740143.1 RNA Sequence

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