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CFAP141 cilia and flagella associated protein 141 [ Homo sapiens (human) ]

Gene ID: 388701, updated on 20-Aug-2022

Summary

Official Symbol
CFAP141provided by HGNC
Official Full Name
cilia and flagella associated protein 141provided by HGNC
Primary source
HGNC:HGNC:32305
See related
Ensembl:ENSG00000163263 AllianceGenome:HGNC:32305
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf189
Expression
Restricted expression toward testis (RPKM 7.3) See more
Orthologs
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Genomic context

See CFAP141 in Genome Data Viewer
Location:
1q21.3
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (154199085..154206333, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (153336317..153343543, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (154171561..154178809, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene tropomyosin 3 Neighboring gene RNA, 7SL, cytoplasmic 431, pseudogene Neighboring gene microRNA 190b Neighboring gene chromosome 1 open reading frame 43 Neighboring gene ubiquitin associated protein 2 like Neighboring gene small nucleolar RNA, H/ACA box 58B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in axonemal microtubule ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
cilia- and flagella-associated protein 141
Names
protein CFAP141
uncharacterized protein C1orf189

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010979.3NP_001010979.1  cilia- and flagella-associated protein 141

    See identical proteins and their annotated locations for NP_001010979.1

    Status: VALIDATED

    Source sequence(s)
    AI052706, HY025946
    Consensus CDS
    CCDS30876.1
    UniProtKB/Swiss-Prot
    A1L4E3, Q5VU69
    Related
    ENSP00000357511.3, ENST00000368525.4
    Conserved Domains (1) summary
    pfam15104
    Location:19100
    DUF4558; Domain of unknown function (DUF4558)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    154199085..154206333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    153336317..153343543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)