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Mcad Medium-chain acyl-CoA dehydrogenase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38864, updated on 8-Nov-2020

Summary

Official Symbol
Mcadprovided by FlyBase
Official Full Name
Medium-chain acyl-CoA dehydrogenaseprovided by FlyBase
Primary source
FLYBASE:FBgn0035811
Locus tag
Dmel_CG12262
Gene type
protein coding
RNA name
Medium-chain acyl-CoA dehydrogenase
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ACAD; CG 12262; CG12262; Dmel\CG12262; MCAD

Genomic context

See Mcad in Genome Data Viewer
Location:
66A10-66A10; 3-21 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7719350..7721472)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7712450..7714572)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Peptidoglycan recognition protein SD Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ankyrin 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sensory neuron membrane protein 2

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
acyl-CoA dehydrogenase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
medium-chain-acyl-CoA dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
medium-chain-acyl-CoA dehydrogenase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
fatty acid beta-oxidation ISS
Inferred from Sequence or Structural Similarity
more info
 
medium-chain fatty acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Medium-chain acyl-CoA dehydrogenase
Names
CG12262-PA
Mcad-PA
acyl-CoA dehdrogenase
medium chain acyl-CoA dehydrogenase
medium-chain acyl-coenzyme A dehydrogenase
probable medium-chain specific acyl-CoA dehydrogenase, mitochondrial
NP_648149.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7719350..7721472
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139892.3NP_648149.1  Medium-chain acyl-CoA dehydrogenase [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648149.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VSA3
    UniProtKB/TrEMBL
    G3KKP7
    Related
    FBpp0076520, FBtr0076808
    Conserved Domains (2) summary
    cd01157
    Location:37414
    MCAD; Medium chain acyl-CoA dehydrogenase
    COG1960
    Location:35411
    CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]
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