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RNF207 ring finger protein 207 [ Homo sapiens (human) ]

Gene ID: 388591, updated on 5-Nov-2017
Official Symbol
RNF207provided by HGNC
Official Full Name
ring finger protein 207provided by HGNC
Primary source
HGNC:HGNC:32947
See related
Ensembl:ENSG00000158286 MIM:616923; Vega:OTTHUMG00000001089
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf188
Expression
Ubiquitous expression in heart (RPKM 5.9), prostate (RPKM 3.0) and 24 other tissues See more
Orthologs
Location:
1p36.31
Exon count:
17
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 1 NC_000001.11 (6205475..6221299)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (6266189..6281359)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene chromodomain helicase DNA binding protein 5 Neighboring gene uncharacterized LOC105376687 Neighboring gene ribosomal protein L22 Neighboring gene uncharacterized LOC107985733 Neighboring gene uncharacterized LOC102724450 Neighboring gene isoprenylcysteine carboxyl methyltransferase Neighboring gene long intergenic non-protein coding RNA 337 Neighboring gene hes family bHLH transcription factor 3

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Common variants at ten loci influence QT interval duration in the QTGEN Study.
NHGRI GWA Catalog
Common variants at ten loci modulate the QT interval duration in the QTSCD Study.
NHGRI GWA Catalog
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ32096, FLJ46380, FLJ46593

Gene Ontology Provided by GOA

Function Evidence Code Pubs
Hsp70 protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
chaperone binding IPI
Inferred from Physical Interaction
more info
PubMed 
ion channel binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
perinuclear region of cytoplasm IMP
Inferred from Mutant Phenotype
more info
PubMed 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207396.2NP_997279.2  RING finger protein 207

    See identical proteins and their annotated locations for NP_997279.2

    Status: VALIDATED

    Source sequence(s)
    AK127700, AL031847, BQ045220, CD673733, DA190055, DB290694, DB636433
    Consensus CDS
    CCDS59.2
    UniProtKB/Swiss-Prot
    Q6ZRF8
    Related
    ENSP00000367173.4, OTTHUMP00000001377, ENST00000377939.4, OTTHUMT00000003669
    Conserved Domains (3) summary
    smart00184
    Location:2563
    RING; Ring finger
    pfam00643
    Location:93145
    zf-B_box; B-box zinc finger
    cl23765
    Location:202321
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p7 Primary Assembly

    Range
    6205475..6221299
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541439.2XP_011539741.1  RING finger protein 207 isoform X1

    Conserved Domains (2) summary
    pfam00643
    Location:161193
    zf-B_box; B-box zinc finger
    cl23765
    Location:250369
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
  2. XM_017001259.1XP_016856748.1  RING finger protein 207 isoform X2

RNA

  1. XR_001737164.1 RNA Sequence

  2. XR_001737158.1 RNA Sequence

  3. XR_001737159.1 RNA Sequence

  4. XR_001737160.1 RNA Sequence

  5. XR_001737162.1 RNA Sequence

  6. XR_946651.2 RNA Sequence

  7. XR_001737163.1 RNA Sequence

  8. XR_946652.2 RNA Sequence

  9. XR_001737161.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    6254831..6270001
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_173795.2: Suppressed sequence

    Description
    NM_173795.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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