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YPEL2 yippee like 2 [ Homo sapiens (human) ]

Gene ID: 388403, updated on 5-Jan-2022

Summary

Official Symbol
YPEL2provided by HGNC
Official Full Name
yippee like 2provided by HGNC
Primary source
HGNC:HGNC:18326
See related
Ensembl:ENSG00000175155 MIM:609723
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FKSG4
Summary
Predicted to enable metal ion binding activity. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in fat (RPKM 5.3), bone marrow (RPKM 5.1) and 25 other tissues See more
Orthologs
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Genomic context

See YPEL2 in Genome Data Viewer
Location:
17q22
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (59331655..59401732)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (57409016..57479090)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase domain containing 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G pseudogene 17 Neighboring gene microRNA 4729 Neighboring gene long intergenic non-protein coding RNA 1476 Neighboring gene uncharacterized LOC105371845 Neighboring gene uncharacterized LOC105371847 Neighboring gene RNA, U4 small nuclear 13, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp761C2021

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein yippee-like 2
Names
DiGeorge syndrome-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005404.4NP_001005404.1  protein yippee-like 2

    See identical proteins and their annotated locations for NP_001005404.1

    Status: VALIDATED

    Source sequence(s)
    AB098736, AC091059, AI540782
    Consensus CDS
    CCDS32695.1
    UniProtKB/Swiss-Prot
    Q96QA6
    Related
    ENSP00000312272.4, ENST00000312655.9
    Conserved Domains (1) summary
    cl13152
    Location:20108
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    59331655..59401732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024621.1XP_016880110.1  protein yippee-like 2 isoform X1

    UniProtKB/Swiss-Prot
    Q96QA6
    Related
    ENSP00000464285.1, ENST00000585166.1
    Conserved Domains (1) summary
    cl13152
    Location:20108
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
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