Format

Send to:

Choose Destination

SBK1 SH3 domain binding kinase 1 [ Homo sapiens (human) ]

Gene ID: 388228, updated on 18-Aug-2020

Summary

Official Symbol
SBK1provided by HGNC
Official Full Name
SH3 domain binding kinase 1provided by HGNC
Primary source
HGNC:HGNC:17699
See related
Ensembl:ENSG00000188322
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SBK
Expression
Broad expression in brain (RPKM 3.9), prostate (RPKM 1.1) and 16 other tissues See more
Orthologs

Genomic context

See SBK1 in Genome Data Viewer
Location:
16p12.1
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (28258628..28323849)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (28270041..28335170)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene exportin 6 Neighboring gene RNY1 pseudogene 10 Neighboring gene glyceraldehyde 3 phosphate dehydrogenase pseudogene 35 Neighboring gene uncharacterized LOC105369182 Neighboring gene nuclear pore complex interacting protein family member B6 Neighboring gene microRNA 6862-1 Neighboring gene eukaryotic translation initiation factor 3 subunit C like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-threonine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase SBK1
Names
SH3-binding domain kinase 1
NP_001019572.1
XP_005255372.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024401.3NP_001019572.1  serine/threonine-protein kinase SBK1

    See identical proteins and their annotated locations for NP_001019572.1

    Status: VALIDATED

    Source sequence(s)
    AY874862
    Consensus CDS
    CCDS32416.1
    UniProtKB/Swiss-Prot
    Q52WX2
    Related
    ENSP00000343248.4, ENST00000341901.5
    Conserved Domains (2) summary
    smart00220
    Location:53316
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13987
    Location:59317
    STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    28258628..28323849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005255315.4XP_005255372.1  serine/threonine-protein kinase SBK1 isoform X1

    Related
    ENSP00000499661.2, ENST00000671413.2
    Conserved Domains (2) summary
    smart00220
    Location:87350
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13987
    Location:93351
    STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1
Support Center