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TMEM179 transmembrane protein 179 [ Homo sapiens (human) ]

Gene ID: 388021, updated on 22-Sep-2022

Summary

Official Symbol
TMEM179provided by HGNC
Official Full Name
transmembrane protein 179provided by HGNC
Primary source
HGNC:HGNC:20137
See related
Ensembl:ENSG00000258986 AllianceGenome:HGNC:20137
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf90; TMEM179A
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 3.6), adrenal (RPKM 2.8) and 1 other tissue See more
Orthologs
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Genomic context

See TMEM179 in Genome Data Viewer
Location:
14q32.33
Exon count:
10
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (104590864..104604772, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (98833645..98847553, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (105057201..105071109, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903395 Neighboring gene chromosome 14 open reading frame 180 Neighboring gene long intergenic non-protein coding RNA 2280 Neighboring gene microRNA 4710

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • FLJ42486

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 179
Names
transmembrane protein 179A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286389.2NP_001273318.1  transmembrane protein 179 isoform 1

    See identical proteins and their annotated locations for NP_001273318.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK124477, AW026835, BX927359
    Consensus CDS
    CCDS66723.1
    UniProtKB/Swiss-Prot
    Q6ZVK1
    Related
    ENSP00000450958.1, ENST00000556573.6
  2. NM_001286390.2NP_001273319.1  transmembrane protein 179 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 3' terminal exon, resulting in a distinct 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AI299168, AK124477, AW026835, BX927359
    Consensus CDS
    CCDS73688.1
    UniProtKB/Swiss-Prot
    Q6ZVK1
    UniProtKB/TrEMBL
    A0A087X0S3
    Related
    ENSP00000483627.1, ENST00000615704.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    104590864..104604772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011536745.3XP_011535047.1  transmembrane protein 179 isoform X2

    See identical proteins and their annotated locations for XP_011535047.1

  2. XM_011536750.2XP_011535052.1  transmembrane protein 179 isoform X3

    See identical proteins and their annotated locations for XP_011535052.1

  3. XM_024449578.2XP_024305346.1  transmembrane protein 179 isoform X1

    Related
    ENSP00000397763.2, ENST00000415614.6

RNA

  1. XR_002957551.2 RNA Sequence

  2. XR_007064011.1 RNA Sequence

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187599.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    148687..162595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    98833645..98847553 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_207379.1: Suppressed sequence

    Description
    NM_207379.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.