U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hex-1 hexagonal-1 [ Neurospora crassa OR74A ]

Gene ID: 3879856, updated on 27-Feb-2025
Gene symbol
hex-1
Gene description
hexagonal-1
Locus tag
NCU08332
See related
FungiDB:NCU08332; VEuPathDB:NCU08332
Gene type
protein coding
RNA name
woronin body major protein
RefSeq status
PROVISIONAL
Organism
Neurospora crassa OR74A (strain: OR74A)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See hex-1 in Genome Data Viewer
Location:
other: I
Exon count:
2
Sequence:
Chromosome: I; NC_026501.1 (5727235..5728917, complement)

Linkage Group I - NC_026501.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene bleomycin hydrolase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene CDP-diacylglycerol-inositol 3-phosphatidyltransferase PIS

Genomic Sequence:
NC_026501.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa. Yuan P, et al. Nat Struct Biol, 2003 Apr. PMID 12640443
  2. A proteomic approach towards the identification of the matrix protein content of the two types of microbodies in Neurospora crassa. Managadze D, et al. Proteomics, 2010 Sep. PMID 20707002
  3. The genome sequence of the filamentous fungus Neurospora crassa. Galagan JE, et al. Nature, 2003 Apr 24. PMID 12712197
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Lattice formation is required for HEX-1 function in Woronin bodies.
    Title: A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa.
  2. HEX1, is the principal protein of Woronin bodies and forms a hexagonal core crystal via oligomerization.
    Title: A proteomic approach towards the identification of the matrix protein content of the two types of microbodies in Neurospora crassa.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ribosome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of translational elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translational termination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Names
woronin body major protein

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_026501.1 Reference assembly

    Range
    5727235..5728917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_958614.3 → XP_963707.1  woronin body major protein [Neurospora crassa OR74A]

    See identical proteins and their annotated locations for XP_963707.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P87252, Q7RV36
    Conserved Domains (2) summary
    cd04469
    Location:102 → 176
    S1_Hex1; Hex1, S1-like RNA-binding domain. Hex1 protein is the major component of the Woronin body in filamentous fungi. The Woronin body is a dense vesicle and plays a vital role in filamentous fungi cell integrity. When cell damage occurs, Woronin bodies seal ...
    cl30809
    Location:5 → 171
    PLN03107; eukaryotic translation initiation factor 5A; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P87252.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials