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REP15 RAB15 effector protein [ Homo sapiens (human) ]

Gene ID: 387849, updated on 15-Jun-2019

Summary

Official Symbol
REP15provided by HGNC
Official Full Name
RAB15 effector proteinprovided by HGNC
Primary source
HGNC:HGNC:33748
See related
Ensembl:ENSG00000174236 MIM:610848
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RAB15EP
Summary
The protein encoded by this intronless gene interacts with GTP-bound Rab15 and is involved in recycling of transferrin receptor from the endocytic recycling compartment to the cell surface. [provided by RefSeq, Sep 2016]
Orthologs

Genomic context

See REP15 in Genome Data Viewer
Location:
12p11.22
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 12 NC_000012.12 (27696519..27697596)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (27849428..27850566)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene single-pass membrane protein with coiled-coil domains 2 Neighboring gene arginyl-tRNA synthetase pseudogene 1 Neighboring gene PPFIA binding protein 1 Neighboring gene uncharacterized protein C12orf71-like Neighboring gene uncharacterized LOC107984461 Neighboring gene high mobility group box 1 pseudogene 49 Neighboring gene mitochondrial ribosomal protein S35

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
receptor recycling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor recycling IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferrin transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferrin transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
early endosome membrane IEA
Inferred from Electronic Annotation
more info
 
endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
recycling endosome IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029874.3NP_001025045.3  rab15 effector protein

    Status: REVIEWED

    Source sequence(s)
    AC009509
    Consensus CDS
    CCDS31762.1
    Related
    ENSP00000310335.2, ENST00000310791.3

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    27696447..27697596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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