U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SPDYC speedy/RINGO cell cycle regulator family member C [ Homo sapiens (human) ]

Gene ID: 387778, updated on 17-Jun-2024

Summary

Official Symbol
SPDYCprovided by HGNC
Official Full Name
speedy/RINGO cell cycle regulator family member Cprovided by HGNC
Primary source
HGNC:HGNC:32681
See related
Ensembl:ENSG00000204710 MIM:614030; AllianceGenome:HGNC:32681
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RINGOC; Ringo2; SPDYE4
Summary
Enables protein kinase binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SPDYC in Genome Data Viewer
Location:
11q13.1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (65170233..65173374)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (65163546..65166687)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64937704..64940845)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4948 Neighboring gene RNA, U2 small nuclear 23, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3510 Neighboring gene PDCL2 pseudogene 2 Neighboring gene phosphoglycerate mutase 1 pseudogene 8 Neighboring gene hESC enhancers GRCh37_chr11:64949086-64949875 and GRCh37_chr11:64949876-64950664 Neighboring gene CAPN1 antisense RNA 1 Neighboring gene calpain 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
speedy protein C
Names
RINGO C
hSpy/Ringo C
rapid inducer of G2/M progression in oocytes C
speedy homolog C

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008778.3NP_001008778.2  speedy protein C

    Status: VALIDATED

    Source sequence(s)
    AP003068
    Consensus CDS
    CCDS31606.2
    UniProtKB/Swiss-Prot
    B2RP32, B7ZMH7, Q5MJ68
    Related
    ENSP00000366390.3, ENST00000377185.3
    Conserved Domains (1) summary
    pfam11357
    Location:38168
    Spy1; Cell cycle regulatory protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    65170233..65173374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017710.2XP_016873199.1  speedy protein C isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    65163546..65166687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054368737.1XP_054224712.1  speedy protein C isoform X1