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FIBIN fin bud initiation factor homolog [ Homo sapiens (human) ]

Gene ID: 387758, updated on 13-May-2022

Summary

Official Symbol
FIBINprovided by HGNC
Official Full Name
fin bud initiation factor homologprovided by HGNC
Primary source
HGNC:HGNC:33747
See related
Ensembl:ENSG00000176971 MIM:617085; AllianceGenome:HGNC:33747
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable protein homodimerization activity. Predicted to act upstream of or within protein kinase C signaling; response to dexamethasone; and response to manganese ion. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See FIBIN in Genome Data Viewer
Location:
11p14.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (26994112..26997087)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (27134604..27137579)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (27015659..27018634)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene 11p14.2 distal LINE-mediated recombination region Neighboring gene uncharacterized LOC124902650 Neighboring gene BBOX1 antisense RNA 1 Neighboring gene gamma-butyrobetaine hydroxylase 1 Neighboring gene uncharacterized LOC124902651

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC24932

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in protein kinase C signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in response to dexamethasone IEA
Inferred from Electronic Annotation
more info
 
involved_in response to manganese ion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
fin bud initiation factor homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203371.2NP_976249.1  fin bud initiation factor homolog precursor

    See identical proteins and their annotated locations for NP_976249.1

    Status: VALIDATED

    Source sequence(s)
    AA452778, AI755024, BC026873, BQ882486, CB962364, D79377
    Consensus CDS
    CCDS7861.1
    UniProtKB/Swiss-Prot
    Q8TAL6
    Related
    ENSP00000321962.2, ENST00000318627.4
    Conserved Domains (1) summary
    pfam15819
    Location:15210
    Fibin; Fin bud initiation factor homolog

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    26994112..26997087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    27134604..27137579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)