U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SKIDA1 SKI/DACH domain containing 1 [ Homo sapiens (human) ]

Gene ID: 387640, updated on 17-Jun-2024

Summary

Official Symbol
SKIDA1provided by HGNC
Official Full Name
SKI/DACH domain containing 1provided by HGNC
Primary source
HGNC:HGNC:32697
See related
Ensembl:ENSG00000180592 AllianceGenome:HGNC:32697
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DLN-1; C10orf140
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SKIDA1 in Genome Data Viewer
Location:
10p12.31
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (21513475..21525682, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (21532596..21548235, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (21802404..21814611, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902598 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21783452-21784245 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2186 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2187 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2188 Neighboring gene MIR1915 host gene Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21793394-21793626 Neighboring gene microRNA 1915 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2189 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814003-21814646 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814647-21815290 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2191 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2192 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21816390-21816548 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:21817867-21818510 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21822730-21823443 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2196 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2197 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:21824159-21824871 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21825135-21825648 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21840002-21840186 Neighboring gene MLLT10 histone lysine methyltransferase DOT1L cofactor Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21844418-21845000 Neighboring gene RNA, U6 small nuclear 306, pseudogene Neighboring gene solute carrier family 4 member 8 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
SKI/DACH domain-containing protein 1
Names
protein DLN-1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207371.4NP_997254.3  SKI/DACH domain-containing protein 1

    See identical proteins and their annotated locations for NP_997254.3

    Status: VALIDATED

    Source sequence(s)
    AK131456, AL358780, AL834446, BI497298, DB320086
    Consensus CDS
    CCDS44363.1
    UniProtKB/Swiss-Prot
    B1ANA5, E9PAX1, F5H7M0, Q1XH10, Q6ZMX4, Q8N3C3
    Related
    ENSP00000410041.2, ENST00000449193.7
    Conserved Domains (2) summary
    pfam02437
    Location:1095
    Ski_Sno; SKI/SNO/DAC family
    pfam15223
    Location:475906
    DUF4584; Domain of unknown function (DUF4584)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    21513475..21525682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047425204.1XP_047281160.1  SKI/DACH domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    B1ANA5, E9PAX1, F5H7M0, Q1XH10, Q6ZMX4, Q8N3C3
  2. XM_047425205.1XP_047281161.1  SKI/DACH domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    B1ANA5, E9PAX1, F5H7M0, Q1XH10, Q6ZMX4, Q8N3C3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    21532596..21548235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054365848.1XP_054221823.1  SKI/DACH domain-containing protein 1 isoform X2

  2. XM_054365851.1XP_054221826.1  SKI/DACH domain-containing protein 1 isoform X1

  3. XM_054365850.1XP_054221825.1  SKI/DACH domain-containing protein 1 isoform X1

  4. XM_054365849.1XP_054221824.1  SKI/DACH domain-containing protein 1 isoform X3

  5. XM_054365847.1XP_054221822.1  SKI/DACH domain-containing protein 1 isoform X2