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SLC22A25 solute carrier family 22 member 25 [ Homo sapiens (human) ]

Gene ID: 387601, updated on 1-Jun-2020

Summary

Official Symbol
SLC22A25provided by HGNC
Official Full Name
solute carrier family 22 member 25provided by HGNC
Primary source
HGNC:HGNC:32935
See related
Ensembl:ENSG00000196600 MIM:610792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UST6; HIMTP
Expression
Restricted expression toward liver (RPKM 2.7) See more
Orthologs

Genomic context

See SLC22A25 in Genome Data Viewer
Location:
11q12.3
Exon count:
17
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (63162264..63243523, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (62930523..63005415, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene tubulin alpha pseudogene 7 Neighboring gene solute carrier family 22 member 24 Neighboring gene ribosomal protein L29 pseudogene 22 Neighboring gene uncharacterized LOC105369334 Neighboring gene cyclin D2 pseudogene 1 Neighboring gene solute carrier family 22 member 10

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC120420, MGI:2385316, MGI:2442750, MGI:2442751, MGI:3042283, MGI:3605624, MGI:3645714

Gene Ontology Provided by GOA

Function Evidence Code Pubs
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 22 member 25
Names
MGI:2442751, MGI:2385316, MGI:3042283, MGI:3645714, MGI:3605624, MGI:2442750
organic anion transporter UST6
putative UST1-like organic anion transporter

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199352.4NP_955384.3  solute carrier family 22 member 25

    See identical proteins and their annotated locations for NP_955384.3

    Status: VALIDATED

    Source sequence(s)
    AA010320, AP003420, AV660430, AY437532, BC101315
    Consensus CDS
    CCDS31592.1
    UniProtKB/Swiss-Prot
    Q6T423
    Related
    ENSP00000307443.6, ENST00000306494.10
    Conserved Domains (2) summary
    cd06174
    Location:151516
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11525
    2A0119; cation transport protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    63162264..63243523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017686.1XP_016873175.1  solute carrier family 22 member 25 isoform X1

  2. XM_017017692.1XP_016873181.1  solute carrier family 22 member 25 isoform X6

  3. XM_017017696.1XP_016873185.1  solute carrier family 22 member 25 isoform X10

  4. XM_017017690.1XP_016873179.1  solute carrier family 22 member 25 isoform X5

  5. XM_017017684.1XP_016873173.1  solute carrier family 22 member 25 isoform X1

  6. XM_017017685.1XP_016873174.1  solute carrier family 22 member 25 isoform X1

  7. XM_017017691.2XP_016873180.1  solute carrier family 22 member 25 isoform X5

  8. XM_017017689.2XP_016873178.1  solute carrier family 22 member 25 isoform X4

  9. XM_017017688.1XP_016873177.1  solute carrier family 22 member 25 isoform X3

  10. XM_017017694.1XP_016873183.1  solute carrier family 22 member 25 isoform X8

  11. XM_017017693.1XP_016873182.1  solute carrier family 22 member 25 isoform X7

    Conserved Domains (2) summary
    cd06174
    Location:182350
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:4359
    2A0119; cation transport protein
  12. XM_017017687.2XP_016873176.1  solute carrier family 22 member 25 isoform X2

    UniProtKB/Swiss-Prot
    Q6T423
    Conserved Domains (2) summary
    cd06174
    Location:151516
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11525
    2A0119; cation transport protein
  13. XM_017017695.1XP_016873184.1  solute carrier family 22 member 25 isoform X9

RNA

  1. XR_001747863.1 RNA Sequence

  2. XR_001747864.1 RNA Sequence

    Related
    ENST00000528239.5
  3. XR_001747862.1 RNA Sequence

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