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msh2 mutS ortholog 2-like [ Neurospora crassa OR74A ]

Gene ID: 3875790, updated on 12-Oct-2017

Summary

Gene symbol
msh2
Gene description
mutS ortholog 2-like
Locus tag
NCU02230
Gene type
protein coding
RNA name
DNA mismatch repair protein msh-2
RefSeq status
PROVISIONAL
Organism
Neurospora crassa OR74A (strain: OR74A)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; Neurospora

Genomic context

See msh2 in Genome Data Viewer
Location:
other: VII
Exon count:
3
Sequence:
Chromosome: VII; NC_026507.1 (3257889..3261513)

Linkage Group VII - NC_026507.1Genomic Context describing neighboring genes Neighboring gene glycosyl hydrolase Neighboring gene DNA primase small subunit Neighboring gene tRNA (guanine-N(1)-)-methyltransferase Neighboring gene hypothetical protein Neighboring gene geranylgeranyl transferase type I beta subunit Neighboring gene acetylornithine deacetylase

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Mismatch repair, organism-specific biosystem (from KEGG)
    Mismatch repair, organism-specific biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
  • Mismatch repair, conserved biosystem (from KEGG)
    Mismatch repair, conserved biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...

General gene information

Homology

  • Homologs of the msh2 gene: The msh2 gene is conserved in human, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and frog.

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_026507.1 Reference assembly

    Range
    3257889..3261513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_954550.2XP_959643.1  DNA mismatch repair protein msh-2 [Neurospora crassa OR74A]

    See identical proteins and their annotated locations for XP_959643.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13396
    Conserved Domains (6) summary
    cd03285
    Location:623860
    ABC_MSH2_euk; ATP-binding cassette domain of eukaryotic MutS2 homolog
    COG0249
    Location:15861
    MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
    pfam01624
    Location:13123
    MutS_I; MutS domain I
    pfam05188
    Location:135280
    MutS_II; MutS domain II
    pfam05190
    Location:463556
    MutS_IV; MutS family domain IV
    pfam05192
    Location:295437
    MutS_III; MutS domain III
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