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RASL11A RAS like family 11 member A [ Homo sapiens (human) ]

Gene ID: 387496, updated on 1-Jun-2020

Summary

Official Symbol
RASL11Aprovided by HGNC
Official Full Name
RAS like family 11 member Aprovided by HGNC
Primary source
HGNC:HGNC:23802
See related
Ensembl:ENSG00000122035 MIM:612403
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
RASL11A is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008]
Expression
Ubiquitous expression in fat (RPKM 15.1), colon (RPKM 11.1) and 24 other tissues See more
Orthologs

Genomic context

See RASL11A in Genome Data Viewer
Location:
13q12.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (27270830..27275192)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (27844464..27847828)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 102 Neighboring gene ribosomal protein L21 Neighboring gene small nucleolar RNA, H/ACA box 27 Neighboring gene RNA, U6 small nuclear 70, pseudogene Neighboring gene uncharacterized LOC105370126

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
positive regulation of transcription by RNA polymerase I ISS
Inferred from Sequence or Structural Similarity
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
ras-like protein family member 11A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001331126.2NP_001318055.1  ras-like protein family member 11A isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL159977
    UniProtKB/Swiss-Prot
    Q6T310
    Conserved Domains (1) summary
    cd04146
    Location:1156
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families
  2. NM_206827.2NP_996563.1  ras-like protein family member 11A isoform 1

    See identical proteins and their annotated locations for NP_996563.1

    Status: VALIDATED

    Source sequence(s)
    AL159977
    Consensus CDS
    CCDS9321.1
    UniProtKB/Swiss-Prot
    Q6T310
    Related
    ENSP00000241463.4, ENST00000241463.4
    Conserved Domains (1) summary
    cd04146
    Location:29198
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

    Range
    27270830..27275192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449347.1XP_024305115.1  ras-like protein family member 11A isoform X1

    Conserved Domains (1) summary
    cd04146
    Location:1156
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families
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