mettl17 methyltransferase like 17 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mettl17provided by ZNC
Official Full Name: methyltransferase like 17provided by ZNC
Primary source: ZFIN:ZDB-GENE-031118-203
See related: Ensembl:ENSDARG00000103889 AllianceGenome:ZFIN:ZDB-GENE-031118-203
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mett11d1; wu:fc73c11; si:ch211-284o19.10
Summary: Predicted to enable metal ion binding activity and methyltransferase activity. Predicted to act upstream of or within methylation and translation. Predicted to be located in mitochondrion. Orthologous to human METTL17 (methyltransferase like 17). [provided by Alliance of Genome Resources, Mar 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (37827567..37837170, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (37845110..37854711, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc73c11.x1 (e-PCR)
- UniSTS:194393

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: methyltransferase like 17; ribosome assembly protein METTL17, mitochondrial

Names: methyltransferase 11 domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

37827567..37837170 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009298670.3 → XP_009296945.1 ribosome assembly protein METTL17, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A0R4IJY0, A0A8M3AXF5

Related

ENSDARP00000134250.1, ENSDART00000158179.2

Conserved Domains (1) summary

cl17173
Location:159 → 449

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_009298671.4 → XP_009296946.1 ribosome assembly protein METTL17, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A8M9PPZ4

Conserved Domains (1) summary

cl17173
Location:135 → 425

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Reference GRCz11 ALT_DRER_TU_1

Genomic

NW_018394505.1 Reference GRCz11 ALT_DRER_TU_1

Range

9590..19193 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021471253.2 → XP_021326928.1 ribosome assembly protein METTL17, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A0R4IJY0, A0A8M3AXF5

Conserved Domains (1) summary

cl17173
Location:159 → 449

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_021471254.2 → XP_021326929.1 ribosome assembly protein METTL17, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A8M9PPZ4

Conserved Domains (1) summary

cl17173
Location:135 → 425

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...