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itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) [ Danio rerio (zebrafish) ]

Gene ID: 386787, updated on 6-May-2021

Summary

Official Symbol
itga5provided by ZNC
Official Full Name
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)provided by ZNC
Primary source
ZFIN:ZDB-GENE-031116-52
See related
Ensembl:ENSDARG00000006353
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb66; sb:cb665; wu:fe02h07
Orthologs
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Genomic context

See itga5 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
30
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (33447625..33558158, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (33521094..33631627, complement)
103 previous assembly Zv9 (GCF_000002035.4) 23 NC_007134.5 (33661296..33771829, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 48 member 1a Neighboring gene Rap guanine nucleotide exchange factor (GEF) 3 Neighboring gene cysteine-serine-rich nuclear protein 2 Neighboring gene transcription factor CP2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables fibronectin binding IGI
Inferred from Genetic Interaction
more info
PubMed 
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within adrenal gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within axis elongation involved in somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell migration involved in sprouting angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic viscerocranium morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within extracellular matrix assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within glial cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lens fiber cell morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lens morphogenesis in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within somite rostral/caudal axis specification IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within somitogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within vasculature development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within vasculature development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
integrin alpha-5
Names
fibronectin receptor alpha subunit
integrin alpha5
polypterus

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004288.2NP_001004288.2  integrin alpha-5 precursor

    See identical proteins and their annotated locations for NP_001004288.2

    Status: VALIDATED

    Source sequence(s)
    AY550244, CR293512, EB775387
    UniProtKB/TrEMBL
    Q5I2A9, Q6QAF3
    Related
    ENSDARP00000027718.9, ENSDART00000018301.11
    Conserved Domains (3) summary
    smart00191
    Location:375430
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:479926
    Integrin_alpha2; Integrin alpha
    pfam13517
    Location:269332
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    33447625..33558158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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