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Slitrk3 SLIT and NTRK-like family, member 3 [ Mus musculus (house mouse) ]

Gene ID: 386750, updated on 5-Feb-2019

Summary

Official Symbol
Slitrk3provided by MGI
Official Full Name
SLIT and NTRK-like family, member 3provided by MGI
Primary source
MGI:MGI:2679447
See related
Ensembl:ENSMUSG00000048304
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ST3
Expression
Biased expression in frontal lobe adult (RPKM 4.8), cortex adult (RPKM 4.0) and 8 other tissues See more
Orthologs

Genomic context

See Slitrk3 in Genome Data Viewer
Location:
3; 3 E3
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (73047247..73057881, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (72852047..72860865, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene histocompatibility 2, M region locus 11 pseudogene Neighboring gene sucrase isomaltase (alpha-glucosidase) Neighboring gene predicted gene, 20754 Neighboring gene RIKEN cDNA 4930509J09 gene Neighboring gene butyrylcholinesterase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axonogenesis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of synapse assembly IDA
Inferred from Direct Assay
more info
PubMed 
regulation of presynapse assembly EXP
Inferred from Experiment
more info
PubMed 
regulation of presynapse assembly IDA
Inferred from Direct Assay
more info
PubMed 
regulation of presynapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of presynapse assembly ISO
Inferred from Sequence Orthology
more info
 
synaptic membrane adhesion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
GABA-ergic synapse EXP
Inferred from Experiment
more info
PubMed 
GABA-ergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
GABA-ergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
GABA-ergic synapse ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
integral component of postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of postsynaptic membrane EXP
Inferred from Experiment
more info
PubMed 
integral component of postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of postsynaptic specialization membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SLIT and NTRK-like protein 3
Names
slit and trk like gene 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357851.1NP_001344780.1  SLIT and NTRK-like protein 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC102396, AK139438
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat
  2. NM_198864.3NP_942564.2  SLIT and NTRK-like protein 3 precursor

    See identical proteins and their annotated locations for NP_942564.2

    Status: VALIDATED

    Source sequence(s)
    AC102396, AK139378, BC066059, BE945544
    Consensus CDS
    CCDS17410.1
    UniProtKB/Swiss-Prot
    Q810B9
    Related
    ENSMUSP00000141236.1, ENSMUST00000192477.1
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    73047247..73057881 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501642.2XP_006501705.1  SLIT and NTRK-like protein 3 isoform X1

    UniProtKB/Swiss-Prot
    Q810B9
    Related
    ENSMUSP00000088561.4, ENSMUST00000059407.8
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat
  2. XM_006501641.2XP_006501704.1  SLIT and NTRK-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006501704.1

    UniProtKB/Swiss-Prot
    Q810B9
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat
  3. XM_006501640.2XP_006501703.1  SLIT and NTRK-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006501703.1

    UniProtKB/Swiss-Prot
    Q810B9
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat
  4. XM_006501639.2XP_006501702.1  SLIT and NTRK-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006501702.1

    UniProtKB/Swiss-Prot
    Q810B9
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat
  5. XM_006501638.1XP_006501701.1  SLIT and NTRK-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006501701.1

    UniProtKB/Swiss-Prot
    Q810B9
    Conserved Domains (3) summary
    smart00082
    Location:563598
    LRRCT; Leucine rich repeat C-terminal domain
    sd00033
    Location:82103
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:106162
    LRR_8; Leucine rich repeat
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