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CHKB-CPT1B CHKB-CPT1B readthrough (NMD candidate) [ Homo sapiens (human) ]

Gene ID: 386593, updated on 13-May-2022

Summary

Official Symbol
CHKB-CPT1Bprovided by HGNC
Official Full Name
CHKB-CPT1B readthrough (NMD candidate)provided by HGNC
Primary source
HGNC:HGNC:41998
See related
Ensembl:ENSG00000254413 AllianceGenome:HGNC:41998
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CPT1B; CPT1-M; CPTI-M; CHKL-CPT1B
Summary
The genes CHKB and CPT1B are adjacent on chromosome 22 and read-through transcripts are expressed that include exons from both loci. The read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to express proteins. [provided by RefSeq, Jun 2009]
Expression
Broad expression in heart (RPKM 47.4), testis (RPKM 36.6) and 24 other tissues See more
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Genomic context

See CHKB-CPT1B in Genome Data Viewer
Location:
22q13.33
Exon count:
30
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (50568861..50582999, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (51079388..51093527, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (51007290..51021428, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene kelch domain containing 7B Neighboring gene synaptonemal complex central element protein 3 Neighboring gene uncharacterized LOC107985568 Neighboring gene carnitine palmitoyltransferase 1B Neighboring gene Sharpr-MPRA regulatory region 1531 Neighboring gene choline kinase beta Neighboring gene CHKB divergent transcript Neighboring gene mitogen-activated protein kinase 8 interacting protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Readthrough CHKB-CPT1B

Included genes: CHKB, CPT1B

Other Names

  • CHKB-CPT1B readthrough (non-protein coding)
  • CPT I
  • Carnitine palmitoyltransferase 1B
  • Carnitine palmitoyltransferase I-like protein
  • choline kinase-like, carnitine palmitoyltransferase 1B (muscle) transcription unit

Clone Names

  • FLJ56256, KIAA1670, MGC149140

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027928.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AB051457, CA312186, U62317
    Related
    ENST00000492556.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    50568861..50582999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    51079388..51093527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_003100.1: Suppressed sequence

    Description
    NG_003100.1: This RefSeq was permanently suppressed because it is out of scope for readthrough loci.