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Hsp83 Heat shock protein 83 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38389, updated on 26-Aug-2021

Summary

Official Symbol
Hsp83provided by FlyBase
Official Full Name
Heat shock protein 83provided by FlyBase
Primary source
FLYBASE:FBgn0001233
Locus tag
Dmel_CG1242
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
143198_at; 83; 83K HSP; anon-EST:Liang-2.53; anon-WO0068693; anon-WO0140519.209; CG1242; clone 2.53; Dmel\CG1242; DMHSP82; DmHsp83; E(sev)3A; E(sina)2; en(lz)3C/4C; hsp82; Hsp82; HSP82; hsp83; HSP83; hsp84; hsp90; Hsp90; HSP90; HSP90A1; l(3)j5C2; ms(3)08445; ORF1; P02828; stc; Su(Raf)3A
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Genomic context

See Hsp83 in Genome Data Viewer
Location:
63B11-63B11; 3-6 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3192969..3197059)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3192969..3197059)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene gryzun Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Hsp83 gene: The Hsp83 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP hydrolysis activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables TPR domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables disordered domain specific binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables insulin receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to heat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to heat ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in centrosome cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cold acclimation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in negative regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in pole plasm mRNA localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of insulin receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of neuroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of small RNA loading onto RISC IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of small RNA loading onto RISC IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in proteasome assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein folding ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein folding TAS
Traceable Author Statement
more info
PubMed 
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of circadian sleep/wake cycle, sleep IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of circadian sleep/wake cycle, sleep TAS
Traceable Author Statement
more info
PubMed 
involved_in response to heat IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
part_of chaperone complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of endoplasmic reticulum chaperone complex IPI
Inferred from Physical Interaction
more info
PubMed 
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in polytene chromosome interband IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
heat shock protein 83
Names
CG1242-PA
CG1242-PB
Hsp83-PA
Hsp83-PB
enhancer of seven in absentia 2
enhancer of sevenless 3A
heat-shock protein 90 kDa
hsp83
scratch

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3192969..3197059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274433.1NP_001261362.1  heat shock protein 83, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261362.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02828
    UniProtKB/TrEMBL
    M9PBL3
    Related
    FBpp0305095, FBtr0332873
    Conserved Domains (3) summary
    smart00387
    Location:28179
    HATPase_c; Histidine kinase-like ATPases
    PTZ00272
    Location:6717
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
    pfam00183
    Location:184706
    HSP90; Hsp90 protein
  2. NM_079175.4NP_523899.1  heat shock protein 83, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523899.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02828
    UniProtKB/TrEMBL
    M9PBL3
    Related
    FBpp0072904, FBtr0073040
    Conserved Domains (3) summary
    smart00387
    Location:28179
    HATPase_c; Histidine kinase-like ATPases
    PTZ00272
    Location:6717
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
    pfam00183
    Location:184706
    HSP90; Hsp90 protein
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