Fdxacb1 ferredoxin-fold anticodon binding domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fdxacb1provided by MGI
Official Full Name: ferredoxin-fold anticodon binding domain containing 1provided by MGI
Primary source: MGI:MGI:3584513
See related: Ensembl:ENSMUSG00000037845 AllianceGenome:MGI:3584513
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D630004A14Rik
Summary: Predicted to enable rRNA (uridine-N3-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human FDXACB1 (ferredoxin-fold anticodon binding domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in liver E14 (RPKM 4.0), placenta adult (RPKM 3.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9; 9 A5.3

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (50679538..50683981)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (50768238..50772670)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

D630004A14Rik is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Title: Tissue expression patterns identify mouse cilia genes.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

General gene information

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Homology

Homologs of the Fdxacb1 gene: The Fdxacb1 gene is conserved in human, chimpanzee, dog, cow, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline: 475 organisms have orthologs with human gene Fdxacb1
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables rRNA (uridine-N3-)-methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Process	Evidence Code	Pubs
involved_in rRNA base methylation	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: ferredoxin-fold anticodon-binding domain-containing protein 1 homolog

Names: FDX-ACDB domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198675.2 → NP_941077.2 ferredoxin-fold anticodon-binding domain-containing protein 1 homolog

See identical proteins and their annotated locations for NP_941077.2

Status: VALIDATED

Source sequence(s)

AK085276, BY141558

Consensus CDS

CCDS23174.1

UniProtKB/Swiss-Prot

Q3UY23, Q8BZH7

Related

ENSMUSP00000037082.7, ENSMUST00000042391.13

Conserved Domains (2) summary

smart00896
Location:528 → 622

FDX-ACB; Ferredoxin-fold anticodon binding domain

pfam10354
Location:7 → 176

DUF2431; Domain of unknown function (DUF2431)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000075.7 Reference GRCm39 C57BL/6J

Range

50679538..50683981

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036155098.1 → XP_036010991.1 ferredoxin-fold anticodon-binding domain-containing protein 1 homolog isoform X1

Conserved Domains (2) summary

PLN02788
Location:436 → 569

PLN02788; phenylalanine-tRNA synthetase

pfam10354
Location:7 → 176

DUF2431; Domain of unknown function (DUF2431)