RabX5 RabX5 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: RabX5provided by FlyBase
Official Full Name: RabX5provided by FlyBase
Primary source: FLYBASE:FBgn0035255
Locus tag: Dmel_CG7980
See related: AllianceGenome:FB:FBgn0035255
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7980; Dmel\CG7980; DmRabX5; Q9W0A7; rabX5
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in Rab protein signal transduction and vesicle-mediated transport. Located in synapse. Is expressed in adult head; eye photoreceptor cell; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in orofaciodigital syndrome XX. Orthologous to human RAB34 (RAB34, member RAS oncogene family) and RAB36 (RAB36, member RAS oncogene family). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (1668901..1670108, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (1668901..1670108, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in Rab protein signal transduction	ISS Inferred from Sequence or Structural Similarity more info
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in synapse	IDA Inferred from Direct Assay more info	PubMed
located_in vesicle	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain