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Adgrg5 adhesion G protein-coupled receptor G5 [ Mus musculus (house mouse) ]

Gene ID: 382045, updated on 16-Oct-2021

Summary

Official Symbol
Adgrg5provided by MGI
Official Full Name
adhesion G protein-coupled receptor G5provided by MGI
Primary source
MGI:MGI:2685955
See related
Ensembl:ENSMUSG00000061577
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PGR27; Gm1109; Gpr114
Expression
Biased expression in spleen adult (RPKM 15.2), thymus adult (RPKM 10.3) and 8 other tissues See more
Orthologs
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Genomic context

See Adgrg5 in Genome Data Viewer
Location:
8; 8 C5
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (95648439..95669921)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (94921811..94943293)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (97447594..97467190)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) II (DNA directed) polypeptide C Neighboring gene docking protein 4 Neighboring gene coiled-coil domain containing 102A Neighboring gene predicted gene, 30968 Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene predicted gene, 51544 Neighboring gene adhesion G protein-coupled receptor G3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adhesion G-protein coupled receptor G5
Names
G protein coupled receptor Gpr114
G protein-coupled receptor 114
G-protein coupled receptor PGR27
probable G-protein coupled receptor 114

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033468.3NP_001028640.2  adhesion G-protein coupled receptor G5 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001028640.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has two alternate splice sites in the 5' UTR and CDS respectively, as compared to variant 1. The resulting isoform (2) lacks an internal amino acid, as compared to isoform 1.
    Source sequence(s)
    AK028878, BC144851, BY547428
    Consensus CDS
    CCDS22552.1
    UniProtKB/Swiss-Prot
    Q3V3Z3
    Related
    ENSMUSP00000074155.4, ENSMUST00000074570.10
    Conserved Domains (3) summary
    cd14964
    Location:243267
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:184228
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:241513
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. NM_001145972.1NP_001139444.1  adhesion G-protein coupled receptor G5 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001139444.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK028878, BC144851, BY547428
    Consensus CDS
    CCDS52637.1
    UniProtKB/Swiss-Prot
    Q3V3Z3
    Related
    ENSMUSP00000132628.2, ENSMUST00000166802.9
    Conserved Domains (3) summary
    cd14964
    Location:244268
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:184228
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:242514
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    95648439..95669921
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312886.1XP_017168375.1  adhesion G-protein coupled receptor G5 isoform X2

    UniProtKB/Swiss-Prot
    Q3V3Z3
    Conserved Domains (3) summary
    cd14964
    Location:244268
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:184228
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:242514
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. XM_017312885.1XP_017168374.1  adhesion G-protein coupled receptor G5 isoform X2

    UniProtKB/Swiss-Prot
    Q3V3Z3
    Conserved Domains (3) summary
    cd14964
    Location:244268
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:184228
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:242514
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. XM_011248425.1XP_011246727.1  adhesion G-protein coupled receptor G5 isoform X3

    See identical proteins and their annotated locations for XP_011246727.1

    Conserved Domains (3) summary
    cd14964
    Location:189214
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:130174
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:188460
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  4. XM_017312884.1XP_017168373.1  adhesion G-protein coupled receptor G5 isoform X2

    UniProtKB/Swiss-Prot
    Q3V3Z3
    Conserved Domains (3) summary
    cd14964
    Location:244268
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:184228
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:242514
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  5. XM_011248422.1XP_011246724.1  adhesion G-protein coupled receptor G5 isoform X1

    See identical proteins and their annotated locations for XP_011246724.1

    UniProtKB/Swiss-Prot
    Q3V3Z3
    Conserved Domains (3) summary
    cd14964
    Location:243267
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam01825
    Location:184228
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:241513
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
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