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Gse1 genetic suppressor element 1, coiled-coil protein [ Mus musculus (house mouse) ]

Gene ID: 382034, updated on 26-Sep-2022

Summary

Official Symbol
Gse1provided by MGI
Official Full Name
genetic suppressor element 1, coiled-coil proteinprovided by MGI
Primary source
MGI:MGI:1098275
See related
Ensembl:ENSMUSG00000031822 AllianceGenome:MGI:1098275
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0182; 2210013I18Rik
Summary
Orthologous to human GSE1 (Gse1 coiled-coil protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 46.5), colon adult (RPKM 18.1) and 27 other tissues See more
Orthologs
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Genomic context

See Gse1 in Genome Data Viewer
Location:
8; 8 E1
Exon count:
23
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120955233..121308122)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (120228501..120581383)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A330074K22 gene Neighboring gene CBY1 interacting BAR domain containing 2 Neighboring gene VISTA enhancer mm196 Neighboring gene VISTA enhancer mm1642 Neighboring gene predicted gene, 32968 Neighboring gene VISTA enhancer mm99 Neighboring gene predicted gene, 39264 Neighboring gene VISTA enhancer mm1674 Neighboring gene predicted gene, 51556 Neighboring gene RIKEN cDNA 1700016A09 gene Neighboring gene microRNA 7687 Neighboring gene RIKEN cDNA 1190005I06 gene Neighboring gene predicted gene 10614 Neighboring gene GINS complex subunit 2 (Psf2 homolog) Neighboring gene predicted gene, 27021 Neighboring gene predicted gene, 33075

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC58013

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
genetic suppressor element 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145896.1NP_001139368.1  genetic suppressor element 1 isoform 2

    See identical proteins and their annotated locations for NP_001139368.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and contains an alternate 5' coding region, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AI854638, AK042915, BC043094, BY766823
    Consensus CDS
    CCDS52688.1
    UniProtKB/Swiss-Prot
    Q3U3C9, Q8CCF2
    Related
    ENSMUSP00000112981.2, ENSMUST00000118136.2
    Conserved Domains (2) summary
    pfam12540
    Location:732872
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:11381196
    BST2; Bone marrow stromal antigen 2
  2. NM_001145897.1NP_001139369.1  genetic suppressor element 1 isoform 3

    See identical proteins and their annotated locations for NP_001139369.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream translational start codon, compared to variant 1. The encoded isoform (3) is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AI854638, AK033263, BB624394, BC043094
    Consensus CDS
    CCDS52689.1
    UniProtKB/Swiss-Prot
    Q3U3C9
    Related
    ENSMUSP00000113577.2, ENSMUST00000120493.8
    Conserved Domains (1) summary
    pfam12540
    Location:729869
    DUF3736; Protein of unknown function (DUF3736)
  3. NM_198671.2NP_941073.2  genetic suppressor element 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AI854638, BC043094
    Consensus CDS
    CCDS52687.1
    UniProtKB/Swiss-Prot
    Q3U3C9
    Related
    ENSMUSP00000034279.9, ENSMUST00000034279.16
    Conserved Domains (1) summary
    pfam12540
    Location:742883
    DUF3736; Protein of unknown function (DUF3736)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    120955233..121308122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531145.5XP_006531208.3  genetic suppressor element 1 isoform X1

    Conserved Domains (2) summary
    pfam12540
    Location:14421582
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:18481906
    BST2; Bone marrow stromal antigen 2
  2. XM_006531146.5XP_006531209.3  genetic suppressor element 1 isoform X2

    Conserved Domains (2) summary
    pfam12540
    Location:14421582
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:18121870
    BST2; Bone marrow stromal antigen 2
  3. XM_006531147.4XP_006531210.3  genetic suppressor element 1 isoform X3

    Conserved Domains (3) summary
    PHA03247
    Location:633965
    PHA03247; large tegument protein UL36; Provisional
    pfam12540
    Location:13691509
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:17751833
    BST2; Bone marrow stromal antigen 2
  4. XM_030243649.2XP_030099509.1  genetic suppressor element 1 isoform X5

    Conserved Domains (2) summary
    pfam12540
    Location:742882
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:11121170
    BST2; Bone marrow stromal antigen 2
  5. XM_036154145.1XP_036010038.1  genetic suppressor element 1 isoform X8

    Conserved Domains (1) summary
    pfam12540
    Location:669809
    DUF3736; Protein of unknown function (DUF3736)
  6. XM_006531148.5XP_006531211.1  genetic suppressor element 1 isoform X6

    Conserved Domains (2) summary
    pfam12540
    Location:669809
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:10751133
    BST2; Bone marrow stromal antigen 2
  7. XM_036154143.1XP_036010036.1  genetic suppressor element 1 isoform X4

    Conserved Domains (1) summary
    pfam12540
    Location:729869
    DUF3736; Protein of unknown function (DUF3736)
  8. XM_030243648.1XP_030099508.1  genetic suppressor element 1 isoform X4

    Conserved Domains (1) summary
    pfam12540
    Location:729869
    DUF3736; Protein of unknown function (DUF3736)
  9. XM_036154144.1XP_036010037.1  genetic suppressor element 1 isoform X4

    Conserved Domains (1) summary
    pfam12540
    Location:729869
    DUF3736; Protein of unknown function (DUF3736)
  10. XM_030243647.1XP_030099507.1  genetic suppressor element 1 isoform X4

    Conserved Domains (1) summary
    pfam12540
    Location:729869
    DUF3736; Protein of unknown function (DUF3736)
  11. XM_006531149.5XP_006531212.1  genetic suppressor element 1 isoform X7

    Conserved Domains (2) summary
    pfam12540
    Location:659799
    DUF3736; Protein of unknown function (DUF3736)
    pfam16716
    Location:10651123
    BST2; Bone marrow stromal antigen 2