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Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 [ Mus musculus (house mouse) ]

Gene ID: 382030, updated on 4-Dec-2022

Summary

Official Symbol
Cnep1r1provided by MGI
Official Full Name
CTD nuclear envelope phosphatase 1 regulatory subunit 1provided by MGI
Primary source
MGI:MGI:1921981
See related
Ensembl:ENSMUSG00000036810 AllianceGenome:MGI:1921981
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NEP1-R1; Tmem188; 5033428A16Rik
Summary
Predicted to be involved in positive regulation of protein dephosphorylation; positive regulation of triglyceride biosynthetic process; and protein localization to nucleus. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in cytosol and nuclear membrane. Predicted to be part of Nem1-Spo7 phosphatase complex. Predicted to be active in cytoplasm. Orthologous to human CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 12.6), CNS E11.5 (RPKM 10.5) and 28 other tissues See more
Orthologs
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Genomic context

See Cnep1r1 in Genome Data Viewer
Location:
8; 8 C3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (88845344..88861825)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (88118716..88135197)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39217 Neighboring gene predicted gene 2716 Neighboring gene RAB11a, member RAS oncogene family pseudogene Neighboring gene microRNA 7071 Neighboring gene HEAT repeat containing 3 Neighboring gene terminal nucleotidyltransferase 4B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC171143

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of Nem1-Spo7 phosphatase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Nem1-Spo7 phosphatase complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nuclear envelope phosphatase-regulatory subunit 1
Names
transmembrane protein 188

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029074.3NP_083350.2  nuclear envelope phosphatase-regulatory subunit 1

    See identical proteins and their annotated locations for NP_083350.2

    Status: VALIDATED

    Source sequence(s)
    AC126034, AK146578, BY124150
    Consensus CDS
    CCDS52628.1
    UniProtKB/Swiss-Prot
    Q3UJ81, Q9D3Q4
    UniProtKB/TrEMBL
    A0A6P5Q7S9, A0A8C6MW64
    Related
    ENSMUSP00000092839.4, ENSMUST00000095214.10
    Conserved Domains (1) summary
    pfam09771
    Location:5122
    Tmemb_18A; Transmembrane protein 188

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    88845344..88861825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248420.2XP_011246722.1  nuclear envelope phosphatase-regulatory subunit 1 isoform X1

    Conserved Domains (1) summary
    pfam09771
    Location:5112
    Tmemb_18A; Transmembrane protein 188
  2. XM_011248421.2XP_011246723.1  nuclear envelope phosphatase-regulatory subunit 1 isoform X2

    See identical proteins and their annotated locations for XP_011246723.1

    Related
    ENSMUSP00000113207.2, ENSMUST00000117775.2
    Conserved Domains (1) summary
    pfam09771
    Location:5112
    Tmemb_18A; Transmembrane protein 188