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Itgad integrin, alpha D [ Mus musculus (house mouse) ]

Gene ID: 381924, updated on 6-Feb-2017
Official Symbol
Itgadprovided by MGI
Official Full Name
integrin, alpha Dprovided by MGI
Primary source
MGI:MGI:3578624
See related
Ensembl:ENSMUSG00000070369 Vega:OTTMUSG00000042024
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cd11d
Orthologs
Location:
7; 7 F3
Exon count:
31
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (128173933..128205504)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (135317460..135349018)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene integrin alpha X Neighboring gene mitochondrial carrier triple repeat 1 pseudogene Neighboring gene RIKEN cDNA 4931431B13 gene Neighboring gene predicted gene, 39091 Neighboring gene cytochrome c oxidase subunit VIa polypeptide 2 Neighboring gene RIKEN cDNA 9130023H24 gene Neighboring gene armadillo repeat containing 5 Neighboring gene transforming growth factor beta 1 induced transcript 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
activated T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
heterotypic cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integrin complex IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029872.3NP_001025043.3  integrin alpha-D precursor

    See identical proteins and their annotated locations for NP_001025043.3

    Status: VALIDATED

    Source sequence(s)
    AC124566, AW495405
    Consensus CDS
    CCDS21890.2
    UniProtKB/TrEMBL
    E9PXZ7
    Related
    ENSMUSP00000033051, OTTMUSP00000061405, ENSMUST00000033051, OTTMUST00000110161
    Conserved Domains (4) summary
    smart00191
    Location:559614
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:156367
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam00357
    Location:11651178
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:6661003
    Integrin_alpha2; Integrin alpha

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    128173933..128205504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507971.3XP_006508034.1  integrin alpha-D isoform X1

    Conserved Domains (4) summary
    smart00191
    Location:549604
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:156357
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam00357
    Location:11551168
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:656993
    Integrin_alpha2; Integrin alpha
  2. XM_006507972.3XP_006508035.1  integrin alpha-D isoform X2

    UniProtKB/TrEMBL
    H3BKX8
    Related
    ENSMUSP00000135572, OTTMUSP00000061406, ENSMUST00000177111, OTTMUST00000110162
    Conserved Domains (4) summary
    smart00191
    Location:523578
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:156331
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam00357
    Location:11291142
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:630967
    Integrin_alpha2; Integrin alpha

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001177632.1: Suppressed sequence

    Description
    NM_001177632.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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