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Igkv2-112 immunoglobulin kappa variable 2-112 [ Mus musculus (house mouse) ]

Gene ID: 381776, updated on 26-Sep-2022

Summary

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Official Symbol
Igkv2-112provided by MGI
Official Full Name
immunoglobulin kappa variable 2-112provided by MGI
Primary source
MGI:MGI:3644894
See related
Ensembl:ENSMUSG00000076518 IMGT/GENE-DB:IGKV2-112; AllianceGenome:MGI:3644894
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
hg24; Gm5153; EG381776
Summary
Predicted to be involved in immune response. Predicted to act upstream of or within adaptive immune response. Predicted to be part of immunoglobulin complex. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Igkv2-112 in Genome Data Viewer
Location:
6; 6 C1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (68196965..68197689)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (68219981..68220705)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene immunoglobulin kappa chain variable 2-113 Neighboring gene immunoglobulin kappa variable 14-111 Neighboring gene cortactin pseudogene Neighboring gene predicted gene, 25436

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Somatic diversification is required to generate the V kappa genes of MOPC 511 and MOPC 167 myeloma proteins. Gershenfeld HK, et al. Proc Natl Acad Sci U S A, 1981 Dec. PMID 6801657, Free PMC Article
  2. kappa Chain variable region from M167, a phosphorylcholine binding myeloma protein. Rudikoff S, et al. Biochemistry, 1978 Jul 11. PMID 99160
  3. Evolution of a multigene family of V kappa germ line genes. Joho R, et al. EMBO J, 1984 Jan. PMID 6546718, Free PMC Article
  4. Somatic mutation of immunoglobulin light-chain variable-region genes. Selsing E, et al. Cell, 1981 Jul. PMID 6791832
  5. Sequences of 12 monoclonal anti-dinitrophenyl spin-label antibodies for NMR studies. Leahy DJ, et al. Proc Natl Acad Sci U S A, 1988 Jun. PMID 3375235, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Other Names

  • Ig kappa V-region 24
  • immunoglobulin kappa chain variable 2-112
  • immunoglobulin light chain variable region

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
  
involved_in immunoglobulin production IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of immunoglobulin complex IEA
Inferred from Electronic Annotation
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005612.1 

    Range
    665001..665725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    68196965..68197689
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P01626.1 GenPept UniProtKB/Swiss-Prot:P01626
P01627.1 GenPept UniProtKB/Swiss-Prot:P01627
P01628.1 GenPept UniProtKB/Swiss-Prot:P01628

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases