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L1td1 LINE-1 type transposase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 381591, updated on 26-Sep-2022

Summary

Official Symbol
L1td1provided by MGI
Official Full Name
LINE-1 type transposase domain containing 1provided by MGI
Primary source
MGI:MGI:3578435
See related
Ensembl:ENSMUSG00000087166 AllianceGenome:MGI:3578435
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ECAT11
Summary
Predicted to enable single-stranded RNA binding activity. Predicted to be involved in transposition, RNA-mediated. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of ribonucleoprotein complex. Is expressed in ovary and testis. Orthologous to human L1TD1 (LINE1 type transposase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward placenta adult (RPKM 10.8) See more
Orthologs
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Genomic context

See L1td1 in Genome Data Viewer
Location:
4; 4 C6
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (98614991..98626723)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (98726754..98738486)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene PATJ, crumbs cell polarity complex component Neighboring gene predicted gene, 35137 Neighboring gene predicted gene, 35073 Neighboring gene KN motif and ankyrin repeat domains 4 Neighboring gene RIKEN cDNA I0C0044D17 gene Neighboring gene KN motif and ankyrin repeat domains 4, opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in transposition, RNA-mediated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
LINE-1 type transposase domain-containing protein 1
Names
ES cell-associated protein 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081202.1NP_001074671.1  LINE-1 type transposase domain-containing protein 1

    See identical proteins and their annotated locations for NP_001074671.1

    Status: VALIDATED

    Source sequence(s)
    AL670941
    Consensus CDS
    CCDS51235.1
    UniProtKB/Swiss-Prot
    Q3UKY3, Q587J6
    Related
    ENSMUSP00000127504.2, ENSMUST00000154279.3
    Conserved Domains (1) summary
    pfam02994
    Location:519779
    Transposase_22; L1 transposable element

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    98614991..98626723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)