Ctxn2 cortexin 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ctxn2provided by MGI
Official Full Name: cortexin 2provided by MGI
Primary source: MGI:MGI:2139444
See related: Ensembl:ENSMUSG00000074872 AllianceGenome:MGI:2139444
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1638
Summary: Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human CTXN2 (cortexin 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in CNS E18 (RPKM 5.3), cerebellum adult (RPKM 3.4) and 5 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2; 2 F1

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (124978534..124989763)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (125136066..125147843)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Homology

Homologs of the Ctxn2 gene: The Ctxn2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, and zebrafish.
Orthologs from Annotation Pipeline: 464 organisms have orthologs with human gene Ctxn2
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cortexin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001162934.2 → NP_001156406.3 cortexin-2

Status: VALIDATED

Source sequence(s)

AL929451

Consensus CDS

CCDS50692.1

UniProtKB/Swiss-Prot

Q3URE8

Related

ENSMUSP00000097051.3, ENSMUST00000099452.3

Conserved Domains (1) summary

pfam11057
Location:9 → 81

Cortexin; Cortexin of kidney