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Garem1 GRB2 associated regulator of MAPK1 subtype 1 [ Mus musculus (house mouse) ]

Gene ID: 381126, updated on 27-Jan-2018

Summary

Official Symbol
Garem1provided by MGI
Official Full Name
GRB2 associated regulator of MAPK1 subtype 1provided by MGI
Primary source
MGI:MGI:2685790
See related
Ensembl:ENSMUSG00000042680
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Garem; Gm944; C86169; Fam59a; mKIAA4238
Expression
Ubiquitous expression in genital fat pad adult (RPKM 4.4), frontal lobe adult (RPKM 4.4) and 28 other tissues See more
Orthologs

Genomic context

See Garem1 in Genome Data Viewer
Location:
18; 18 A2
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (21127342..21300139, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (21285843..21458640, complement)

Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene ring finger protein 138 Neighboring gene meprin 1 beta Neighboring gene ribosomal protein L27A pseudogene Neighboring gene predicted gene, 41675 Neighboring gene predicted gene 7758

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • KIAA4238

Gene Ontology Provided by MGI

Function Evidence Code Pubs
proline-rich region binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cellular response to epidermal growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
epidermal growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
GRB2-associated and regulator of MAPK protein
Names
GRB2 associated, regulator of MAPK1
GRB2-associated and regulator of MAPK1
family with sequence similarity 59, member A
protein FAM59A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033445.2NP_001028617.2  GRB2-associated and regulator of MAPK protein

    See identical proteins and their annotated locations for NP_001028617.2

    Status: VALIDATED

    Source sequence(s)
    AC127570, AC158774, AK148318
    Consensus CDS
    CCDS29091.1
    UniProtKB/Swiss-Prot
    Q3UFT3
    Related
    ENSMUSP00000048914.6, ENSMUST00000049260.6
    Conserved Domains (2) summary
    cd09525
    Location:808874
    SAM_GAREM; SAM domain of GAREM subfamily
    pfam12736
    Location:32323
    CABIT; Cell-cycle sustaining, positive selection,

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

    Range
    21127342..21300139 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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