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Begain brain-enriched guanylate kinase-associated [ Mus musculus (house mouse) ]

Gene ID: 380785, updated on 31-Jan-2019

Summary

Official Symbol
Begainprovided by MGI
Official Full Name
brain-enriched guanylate kinase-associatedprovided by MGI
Primary source
MGI:MGI:3044626
See related
Ensembl:ENSMUSG00000040867
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm897; BM948371
Expression
Biased expression in cortex adult (RPKM 24.5), frontal lobe adult (RPKM 23.8) and 12 other tissues See more
Orthologs

Genomic context

See Begain in Genome Data Viewer
Location:
12; 12 F1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (109032181..109068251, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (110270392..110306427, complement)

Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene tryptophanyl-tRNA synthetase Neighboring gene WD repeat domain 25 Neighboring gene peptidyl prolyl isomerase H pseudogene Neighboring gene macrophage migration inhibitory factor, pseudogene 7 Neighboring gene delta like non-canonical Notch ligand 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
postsynapse ISO
Inferred from Sequence Orthology
more info
 
presynapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
brain-enriched guanylate kinase-associated protein
Names
brain-enriched guanylate kinase-associated; brain-enriched guanylate kinase-associated protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163175.1NP_001156647.1  brain-enriched guanylate kinase-associated protein

    Status: VALIDATED

    Source sequence(s)
    AK158915, BC080282
    Consensus CDS
    CCDS56862.1
    UniProtKB/Swiss-Prot
    Q68EF6
    UniProtKB/TrEMBL
    F8WIG2
    Related
    ENSMUSP00000140393.2, ENSMUST00000190647.2
    Conserved Domains (1) summary
    cl12013
    Location:41158
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

    Range
    109032181..109068251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516039.2XP_006516102.1  brain-enriched guanylate kinase-associated protein isoform X1

    Conserved Domains (1) summary
    cl12013
    Location:71188
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  2. XM_011244128.2XP_011242430.1  brain-enriched guanylate kinase-associated protein isoform X4

    See identical proteins and their annotated locations for XP_011242430.1

    Conserved Domains (1) summary
    cl12013
    Location:52169
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  3. XM_006516044.2XP_006516107.1  brain-enriched guanylate kinase-associated protein isoform X7

    See identical proteins and their annotated locations for XP_006516107.1

    UniProtKB/Swiss-Prot
    Q68EF6
    Conserved Domains (1) summary
    cl12013
    Location:22139
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  4. XM_006516043.3XP_006516106.1  brain-enriched guanylate kinase-associated protein isoform X6

    Conserved Domains (1) summary
    cl12013
    Location:35152
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  5. XM_006516041.3XP_006516104.1  brain-enriched guanylate kinase-associated protein isoform X3

    Conserved Domains (1) summary
    cl12013
    Location:65182
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  6. XM_006516042.1XP_006516105.1  brain-enriched guanylate kinase-associated protein isoform X5

    Conserved Domains (1) summary
    pfam13094
    Location:1148
    CENP-Q; CENP-Q, a CENPA-CAD centromere complex subunit
  7. XM_006516040.3XP_006516103.1  brain-enriched guanylate kinase-associated protein isoform X2

    Conserved Domains (1) summary
    cl12013
    Location:69186
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  8. XM_011244130.2XP_011242432.1  brain-enriched guanylate kinase-associated protein isoform X7

    See identical proteins and their annotated locations for XP_011242432.1

    UniProtKB/Swiss-Prot
    Q68EF6
    Conserved Domains (1) summary
    cl12013
    Location:22139
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
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