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Cnrip1 cannabinoid receptor interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 380686, updated on 30-Apr-2024

Summary

Official Symbol
Cnrip1provided by MGI
Official Full Name
cannabinoid receptor interacting protein 1provided by MGI
Primary source
MGI:MGI:1917505
See related
Ensembl:ENSMUSG00000044629 AllianceGenome:MGI:1917505
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C2orf32; 1500041B16Rik; 3110054C06Rik; 5330437A18Rik
Summary
Predicted to enable protein C-terminus binding activity and type 1 cannabinoid receptor binding activity. Predicted to be involved in negative regulation of signaling receptor activity. Located in myelin sheath. Is expressed in mesonephros. Orthologous to human CNRIP1 (cannabinoid receptor interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 66.2), whole brain E14.5 (RPKM 33.4) and 12 other tissues See more
Orthologs
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Genomic context

See Cnrip1 in Genome Data Viewer
Location:
11 A2; 11 9.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (17001859..17029372)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (17051859..17079372)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene signal peptide, CUB domain, EGF-like 3 pseudogene Neighboring gene predicted gene, 53668 Neighboring gene STARR-seq mESC enhancer starr_28701 Neighboring gene STARR-seq mESC enhancer starr_28702 Neighboring gene STARR-seq mESC enhancer starr_28703 Neighboring gene 60S ribosomal protein L39 pseudogene Neighboring gene protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) Neighboring gene STARR-seq mESC enhancer starr_28704

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables type 1 cannabinoid receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables type 1 cannabinoid receptor binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in GABA-ergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in myelin sheath HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in presynapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
CB1 cannabinoid receptor-interacting protein 1
Names
CRIP-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029861.3NP_084137.1  CB1 cannabinoid receptor-interacting protein 1

    See identical proteins and their annotated locations for NP_084137.1

    Status: VALIDATED

    Source sequence(s)
    AL606466
    Consensus CDS
    CCDS24447.1
    UniProtKB/Swiss-Prot
    Q3TAC7, Q3UFR2, Q5M8N0
    Related
    ENSMUSP00000050036.6, ENSMUST00000058159.6
    Conserved Domains (1) summary
    pfam15043
    Location:4158
    CNRIP1; CB1 cannabinoid receptor-interacting protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    17001859..17029372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)