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Fastkd5 FAST kinase domains 5 [ Mus musculus (house mouse) ]

Gene ID: 380601, updated on 26-Sep-2022

Summary

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Official Symbol
Fastkd5provided by MGI
Official Full Name
FAST kinase domains 5provided by MGI
Primary source
MGI:MGI:2139469
See related
Ensembl:ENSMUSG00000079043 AllianceGenome:MGI:2139469
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1792
Summary
Predicted to enable rRNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to act upstream of or within mRNA processing. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Is expressed in several structures, including alimentary system; genitourinary system; immune system; nervous system; and nose. Orthologous to human FASTKD5 (FAST kinase domains 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 2.8), CNS E11.5 (RPKM 2.7) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Fastkd5 in Genome Data Viewer
Location:
2; 2 F1
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (130455766..130471922, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (130613846..130630002, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene oxytocin Neighboring gene arginine vasopressin Neighboring gene U box domain containing 5 Neighboring gene leucine zipper, putative tumor suppressor family member 3 Neighboring gene DDRGK domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ13149, KIAA1792, MGC60835

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables rRNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in mitochondrial RNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of mitochondrial mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in mitochondrial nucleoid ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
is_active_in ribonucleoprotein granule IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
FAST kinase domain-containing protein 5, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146084.2 → NP_001139556.2  FAST kinase domain-containing protein 5, mitochondrial

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL731707
    Consensus CDS
    CCDS50713.2
    UniProtKB/Swiss-Prot
    Q5DTV0
    Conserved Domains (3) summary
    smart00952
    Location:697 → 756
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:430 → 499
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:511 → 600
    FAST_2; FAST kinase-like protein, subdomain 2

  2. NM_001377124.1 → NP_001364053.1  FAST kinase domain-containing protein 5, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AL731707
    UniProtKB/Swiss-Prot
    Q5DTV0
    Related
    ENSMUSP00000105891.3, ENSMUST00000110262.3
    Conserved Domains (3) summary
    smart00952
    Location:697 → 756
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:430 → 499
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:511 → 600
    FAST_2; FAST kinase-like protein, subdomain 2

  3. NM_001377125.1 → NP_001364054.1  FAST kinase domain-containing protein 5, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AL731707
    UniProtKB/Swiss-Prot
    Q5DTV0
    Related
    ENSMUSP00000137385.2, ENSMUST00000179273.2
    Conserved Domains (3) summary
    smart00952
    Location:697 → 756
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:430 → 499
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:511 → 600
    FAST_2; FAST kinase-like protein, subdomain 2

  4. NM_198176.3 → NP_937819.3  FAST kinase domain-containing protein 5, mitochondrial

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL731707
    Consensus CDS
    CCDS50713.2
    UniProtKB/Swiss-Prot
    Q5DTV0
    Conserved Domains (3) summary
    smart00952
    Location:697 → 756
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:430 → 499
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:511 → 600
    FAST_2; FAST kinase-like protein, subdomain 2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    130455766..130471922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TMV3.1 GenPept UniProtKB/Swiss-Prot:Q7TMV3

Gene LinkOut

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