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eif2s3.S eukaryotic translation initiation factor 2 subunit gamma S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380257, updated on 5-Sep-2025
Official Symbol
eif2s3.S
Official Full Name
eukaryotic translation initiation factor 2 subunit gamma S homeolog
Primary source
Xenbase:XB-GENE-986368
Locus tag
XELAEV_18014542mg
See related
AllianceGenome:Xenbase:XB-GENE-986368
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
eif2s3
Summary
Predicted to enable several functions, including GTP binding activity; GTPase activity; and translation initiation factor activity. Predicted to act upstream of or within translational initiation. Human ortholog(s) of this gene implicated in MEHMO syndrome. Orthologous to human EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma). [provided by Alliance of Genome Resources, Jul 2025]
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See eif2s3.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (32607556..32631805, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (31666400..31690660, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase domain containing 1 S homeolog Neighboring gene zinc finger protein X-linked S homeolog Neighboring gene acyl-CoA thioesterase 9 S homeolog Neighboring gene spermidine/spermine N1-acetyltransferase 1 S homeolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Clone Names

  • MGC53362

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
eukaryotic translation initiation factor 2 subunit gamma S homeolog
Names
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087096.1 → NP_001080565.1  eukaryotic translation initiation factor 2 subunit gamma S homeolog

    See identical proteins and their annotated locations for NP_001080565.1

    Status: PROVISIONAL

    Source sequence(s)
    BC043966
    UniProtKB/TrEMBL
    A0A974HVD3, Q7ZY57
    Conserved Domains (4) summary
    cd01888
    Location:42 → 248
    eIF2_gamma; Gamma subunit of initiation factor 2 (eIF2 gamma)
    PTZ00327
    Location:13 → 466
    PTZ00327; eukaryotic translation initiation factor 2 gamma subunit; Provisional
    cd03688
    Location:249 → 362
    eIF2_gamma_II; Domain II of the gamma subunit of eukaryotic translation initiation factor 2
    cd15490
    Location:365 → 459
    eIF2_gamma_III; Domain III of eukaryotic initiation factor eIF2 gamma

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    32607556..32631805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018248064.1 → XP_018103553.1  eukaryotic translation initiation factor 2 subunit gamma S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974HVD3, Q7ZY57

  2. XM_018248065.1 → XP_018103554.1  eukaryotic translation initiation factor 2 subunit gamma S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974HVD3, Q7ZY57
Nucleotide Protein Strain
Heading Accession and Version

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