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snx2.S sorting nexin 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 380176, updated on 5-Sep-2025
Official Symbol
snx2.S
Official Full Name
sorting nexin 2 S homeolog
Primary source
Xenbase:XB-GENE-5791539
Locus tag
XELAEV_18010746mg
See related
EnsemblRapid:ENSXLAG00005005906 AllianceGenome:Xenbase:XB-GENE-5791539
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
snx2
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in early endosome membrane and lamellipodium. Predicted to be part of retromer complex. Orthologous to human SNX2 (sorting nexin 2). [provided by Alliance of Genome Resources, Jul 2025]
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See snx2.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (157635642..157666851, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (141713463..141744657, complement)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene peptidylprolyl isomerase C (cyclophilin C) S homeolog Neighboring gene sorting nexin 24 S homeolog Neighboring gene synuclein alpha interacting protein S homeolog Neighboring gene ancient vomeronasal 1 receptor S homeolog Neighboring gene zinc finger protein 474 S homeolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Clone Names

  • MGC64590

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of retromer complex IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
sorting nexin 2 S homeolog

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087015.2 → NP_001080484.1  sorting nexin 2 S homeolog

    See identical proteins and their annotated locations for NP_001080484.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054996
    UniProtKB/TrEMBL
    A0A974DWY1, Q7SY62
    Related
    ENSXLAP00005017696.1, ENSXLAT00005017992.1
    Conserved Domains (3) summary
    cd07282
    Location:142 → 265
    PX_SNX2; The phosphoinositide binding Phox Homology domain of Sorting Nexin 2
    cd07664
    Location:283 → 516
    BAR_SNX2; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 2
    pfam03700
    Location:49 → 112
    Sorting_nexin; Sorting nexin, N-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    157635642..157666851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041573242.1 → XP_041429176.1  sorting nexin 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LIL8, A0A974DWY1
    Related
    ENSXLAP00005017687.1, ENSXLAT00005017983.1
    Conserved Domains (2) summary
    cd07282
    Location:142 → 265
    PX_SNX2; The phosphoinositide binding Phox Homology domain of Sorting Nexin 2
    cl12013
    Location:283 → 520
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein Strain
Heading Accession and Version

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