U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cyp9c1 Cytochrome P450 9c1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37941, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Cyp9c1provided by FlyBase
Official Full Name
Cytochrome P450 9c1provided by FlyBase
Primary source
FLYBASE:FBgn0015040
Locus tag
Dmel_CG3616
See related
AllianceGenome:FB:FBgn0015040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
9c1; CG3616; Cyp9C1; CYP9C1; Dmel\CG3616; P-450; P450
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult head. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Cyp9c1 in Genome Data Viewer
Location:
60D10-60D10; 2-107 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24631063..24632923)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20518586..20520446)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene aarF domain containing kinase 1 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43787 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A glycine insertion in the estrogen-related receptor (ERR) is associated with enhanced expression of three cytochrome P450 genes in transgenic Drosophila melanogaster. Sun W, et al. PLoS One, 2015. PMID 25761142, Free PMC Article
  2. Cytochrome P450 gene clusters in Drosophila melanogaster. Dunkov BC, et al. Mol Gen Genet, 1996 Jun 12. PMID 8676871
  3. Ran participates in deltamethrin stress through regulating the nuclear import of Nrf2. Ge M, et al. Gene, 2021 Feb 15. PMID 33069802
  4. Effects of the adenylate cyclase activator forskolin and its inactive derivative 1,9-dideoxyforskolin on insect cytochrome P-450 dependent steroid hydroxylase activity. Keogh DP, et al. Experientia, 1992 Jan 15. PMID 1737575
  5. Alkaloid metabolism by cytochrome P-450 enzymes in Drosophila melanogaster. Danielson PB, et al. Comp Biochem Physiol B Biochem Mol Biol, 1995 Apr. PMID 7749620

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Transgenic flies, expressing the human ERRa-G allele, constitutively over-express Cyp12d1, Cyp6g2 and Cyp9c1.
    Title: A glycine insertion in the estrogen-related receptor (ERR) is associated with enhanced expression of three cytochrome P450 genes in transgenic Drosophila melanogaster.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cytochrome P450 9c1
Names
CG3616-PA
Cyp9c1-PA
cytochrome P450-9c1
NP_523850.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24631063..24632923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079126.3 → NP_523850.1  cytochrome P450 9c1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523850.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24124, Q9W130
    Related
    FBpp0072228
    Conserved Domains (1) summary
    cl12078
    Location:37 → 514
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3YND4 Q3YND4
Q9W130.1 Q9W130

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools