Ssl Suppressor of Stellate-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Sslprovided by FlyBase
Official Full Name: Suppressor of Stellate-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0015300
Locus tag: Dmel_CG13591
See related: AllianceGenome:FB:FBgn0015300
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: betaCK2tes; CG13591; CK2betates; CKIIb1; Dm-CK2-beta[Tes]; DmCK2betates; Dmel\CG13591; NEST:bs30a09; SSL; Su(Ste)l
Summary: Enables protein kinase regulator activity. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (24499243..24500267, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (20386766..20387790, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Coimmunoprecipitation experiments revealed that the alpha-subunit of the protein kinase CK2 (CK2alpha) was associated with soluble Stellate.
Title: Genetically Derepressed Nucleoplasmic Stellate Protein in Spermatocytes of D. melanogaster interacts with the catalytic subunit of protein kinase 2 and carries histone-like lysine-methylated mark.
SSL gene is expressed in larvae, pupae, and adults, exhibits sexual dimorphism, and mimics properties of the beta subunit of casein kinase II
Title: The Drosophila SSL gene is expressed in larvae, pupae, and adults, exhibits sexual dimorphism, and mimics properties of the beta subunit of casein kinase II.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein kinase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase regulator activity	IDA Inferred from Direct Assay more info	PubMed
enables protein kinase regulator activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of protein kinase CK2 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein kinase CK2 complex	IEA Inferred from Electronic Annotation more info