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Raet1e retinoic acid early transcript 1E [ Mus musculus (house mouse) ]

Gene ID: 379043, updated on 27-Nov-2024

Summary

Official Symbol
Raet1eprovided by MGI
Official Full Name
retinoic acid early transcript 1Eprovided by MGI
Primary source
MGI:MGI:2675273
See related
Ensembl:ENSMUSG00000053219 AllianceGenome:MGI:2675273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within T cell mediated cytotoxicity. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in embryo; embryo endoderm; and midgut. Orthologous to human RAET1G (retinoic acid early transcript 1G) and RAET1L (retinoic acid early transcript 1L). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in liver adult (RPKM 1.1), bladder adult (RPKM 0.9) and 21 other tissues See more
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Genomic context

See Raet1e in Genome Data Viewer
Location:
10 A3; 10 9.89 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (22034441..22059820)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (22158542..22189697)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA E030030I06 gene Neighboring gene aldo-keto reductase family 1, member B3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_26015 Neighboring gene predicted gene 4895 Neighboring gene predicted gene, 26740 Neighboring gene UL16 binding protein 1 pseudogene Neighboring gene histocompatibility 60b

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
retinoic acid early-inducible protein 1-epsilon
Names
Rae-1 epsilon

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359808.1NP_001346737.1  retinoic acid early-inducible protein 1-epsilon precursor

    Status: VALIDATED

    Source sequence(s)
    AK012289, AK131854, FJ594067
    Consensus CDS
    CCDS35865.1
    UniProtKB/Swiss-Prot
    A2RSZ5, Q9CZQ6
    UniProtKB/TrEMBL
    D7F2B6
    Related
    ENSMUSP00000138022.2, ENSMUST00000181645.8
    Conserved Domains (1) summary
    cl08246
    Location:31202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
  2. NM_001359809.1NP_001346738.1  retinoic acid early-inducible protein 1-epsilon precursor

    Status: VALIDATED

    Source sequence(s)
    AK012289, AK131854, FJ594067
    Consensus CDS
    CCDS35865.1
    UniProtKB/Swiss-Prot
    A2RSZ5, Q9CZQ6
    UniProtKB/TrEMBL
    D7F2B6
    Conserved Domains (1) summary
    cl08246
    Location:31202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
  3. NM_198193.3NP_937836.1  retinoic acid early-inducible protein 1-epsilon precursor

    See identical proteins and their annotated locations for NP_937836.1

    Status: VALIDATED

    Source sequence(s)
    AK012289, CV561218, FJ594067
    Consensus CDS
    CCDS35865.1
    UniProtKB/Swiss-Prot
    A2RSZ5, Q9CZQ6
    UniProtKB/TrEMBL
    D7F2B6
    Related
    ENSMUSP00000066627.5, ENSMUST00000065527.11
    Conserved Domains (1) summary
    cl08246
    Location:31202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    22034441..22059820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512780.3XP_006512843.1  retinoic acid early-inducible protein 1-epsilon isoform X1

    See identical proteins and their annotated locations for XP_006512843.1

    UniProtKB/Swiss-Prot
    A2RSZ5, Q9CZQ6
    UniProtKB/TrEMBL
    D7F2B6
    Conserved Domains (1) summary
    cl08246
    Location:31202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
  2. XM_011243179.1XP_011241481.1  retinoic acid early-inducible protein 1-epsilon isoform X1

    See identical proteins and their annotated locations for XP_011241481.1

    UniProtKB/Swiss-Prot
    A2RSZ5, Q9CZQ6
    UniProtKB/TrEMBL
    D7F2B6
    Conserved Domains (1) summary
    cl08246
    Location:31202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
  3. XM_006512782.2XP_006512845.1  retinoic acid early-inducible protein 1-epsilon isoform X1

    See identical proteins and their annotated locations for XP_006512845.1

    UniProtKB/Swiss-Prot
    A2RSZ5, Q9CZQ6
    UniProtKB/TrEMBL
    D7F2B6
    Related
    ENSMUSP00000136032.2, ENSMUST00000178026.2
    Conserved Domains (1) summary
    cl08246
    Location:31202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2