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pah phenylalanine hydroxylase [ Danio rerio (zebrafish) ]

Gene ID: 378962, updated on 12-Mar-2017
Official Symbol
pahprovided by ZNC
Official Full Name
phenylalanine hydroxylaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031006-2
See related
Ensembl:ENSDARG00000020143 Vega:OTTDARG00000017746
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
cb877; zgc:65981; wu:fb02f10
Orthologs
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
105 current GRCz10 (GCF_000002035.5) 4 NC_007115.6 (17402704..17420391, complement)
103 previous assembly Zv9 (GCF_000002035.4) 4 NC_007115.5 (16459864..16477551, complement)

Chromosome 4 - NC_007115.6Genomic Context describing neighboring genes Neighboring gene nucleoporin 37 Neighboring gene PARP1 binding protein Neighboring gene pro-melanin-concentrating hormone Neighboring gene tyrosine hydroxylase 2 Neighboring gene uncharacterized LOC101884203 Neighboring gene achaete-scute family bHLH transcription factor 1a

Markers

Homology

Clone Names

  • MGC65981

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
amino acid binding IEA
Inferred from Electronic Annotation
more info
 
iron ion binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
 
phenylalanine 4-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
L-phenylalanine catabolic process IEA
Inferred from Electronic Annotation
more info
 
aromatic amino acid family metabolic process IEA
Inferred from Electronic Annotation
more info
 
cellular response to estrogen stimulus IDA
Inferred from Direct Assay
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
phenylalanine-4-hydroxylase
NP_956845.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200551.1NP_956845.1  phenylalanine-4-hydroxylase

    See identical proteins and their annotated locations for NP_956845.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056537
    UniProtKB/TrEMBL
    Q6PHI7
    Related
    ENSDARP00000012808, OTTDARP00000018011, ENSDART00000011943, OTTDART00000021381
    Conserved Domains (3) summary
    TIGR01268
    Location:20449
    Phe4hydrox_tetr; phenylalanine-4-hydroxylase, tetrameric form
    cd04931
    Location:19108
    ACT_PAH; ACT domain of the nonheme iron-dependent aromatic amino acid hydroxylase, phenylalanine hydroxylases (PAH)
    pfam00351
    Location:117447
    Biopterin_H; Biopterin-dependent aromatic amino acid hydroxylase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz10 Primary Assembly

Genomic

  1. NC_007115.6 Reference GRCz10 Primary Assembly

    Range
    17402704..17420391 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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