Format

Send to:

Choose Destination

RNF148 ring finger protein 148 [ Homo sapiens (human) ]

Gene ID: 378925, updated on 23-Nov-2021

Summary

Official Symbol
RNF148provided by HGNC
Official Full Name
ring finger protein 148provided by HGNC
Primary source
HGNC:HGNC:22411
See related
Ensembl:ENSG00000235631
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See RNF148 in Genome Data Viewer
Location:
7q31.32
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (122701668..122702922, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (122341722..122342976, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene calcium dependent secretion activator 2 Neighboring gene ribosomal protein S26 pseudogene 31 Neighboring gene ring finger protein 133 Neighboring gene RELA proto-oncogene, NF-kB subunit pseudogene Neighboring gene uncharacterized LOC105375482

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC35222

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198085.2NP_932351.1  RING finger protein 148 precursor

    See identical proteins and their annotated locations for NP_932351.1

    Status: VALIDATED

    Source sequence(s)
    BC029264
    Consensus CDS
    CCDS47692.1
    UniProtKB/Swiss-Prot
    Q8N7C7
    Related
    ENSP00000388207.1, ENST00000434824.2
    Conserved Domains (2) summary
    cd02122
    Location:43177
    PA_GRAIL_like; PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3 ...
    pfam13639
    Location:256299
    zf-RING_2; Ring finger domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    122701668..122702922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center