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FLNB filamin B [ Gallus gallus (chicken) ]

Gene ID: 378913, updated on 5-Sep-2025
Symbol
FLNBprovided by CGNC
Full Name
filamin Bprovided by CGNC
Primary source
CGNC:49141
See related
Ensembl:ENSGALG00010027114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
filamin-B
Orthologs
human mouse all
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See FLNB in Genome Data Viewer
Location:
chromosome: 12
Exon count:
49
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (9034328..9112485)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (9061591..9140039)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene DENN domain containing 6A Neighboring gene uncharacterized LOC121106678 Neighboring gene microRNA 1787 Neighboring gene sarcolemma associated protein Neighboring gene deoxyribonuclease 1 like 3 Neighboring gene abhydrolase domain containing 6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Molecular characterization of a multi-promoter gene encoding a chicken filamin protein. Barry CP, et al. J Biol Chem, 1993 Dec 5. PMID 8244995
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
filamin-B
Names
filamin B, beta (actin binding protein 278)
retina filamin

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030341.3 → NP_001025512.2  filamin-B

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/TrEMBL
    F1N8D4
    Related
    ENSGALP00010039990.1, ENSGALT00010065724.1
    Conserved Domains (3) summary
    smart00557
    Location:1440 → 1533
    IG_FLMN; Filamin-type immunoglobulin domains
    cd00014
    Location:36 → 140
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00630
    Location:1437 → 1527
    Filamin; Filamin/ABP280 repeat

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    9034328..9112485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015292937.4 → XP_015148423.1  filamin-B isoform X3

    UniProtKB/TrEMBL
    A0A1D5NYG3, F1N8D4
    Conserved Domains (2) summary
    smart00557
    Location:1347 → 1436
    IG_FLMN; Filamin-type immunoglobulin domains
    COG5069
    Location:33 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

  2. XM_046899761.1 → XP_046755717.1  filamin-B isoform X3

    UniProtKB/TrEMBL
    A0A1D5NYG3, F1N8D4

  3. XM_046899762.1 → XP_046755718.1  filamin-B isoform X3

    UniProtKB/TrEMBL
    A0A1D5NYG3, F1N8D4
    Related
    ENSGALP00010039991.1, ENSGALT00010065725.1

  4. XM_040646067.2 → XP_040502001.1  filamin-B isoform X4

    UniProtKB/TrEMBL
    F1N8D4
    Related
    ENSGALP00010039997.1, ENSGALT00010065731.1
    Conserved Domains (2) summary
    smart00557
    Location:1347 → 1436
    IG_FLMN; Filamin-type immunoglobulin domains
    COG5069
    Location:33 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

  5. XM_040646065.2 → XP_040501999.1  filamin-B isoform X1

    UniProtKB/TrEMBL
    A0A8V1A9S9, F1N8D4
    Related
    ENSGALP00010039993.1, ENSGALT00010065727.1
    Conserved Domains (2) summary
    smart00557
    Location:1347 → 1436
    IG_FLMN; Filamin-type immunoglobulin domains
    COG5069
    Location:33 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

  6. XM_040646068.2 → XP_040502002.1  filamin-B isoform X5

    UniProtKB/TrEMBL
    F1N8D4
    Conserved Domains (2) summary
    smart00557
    Location:1347 → 1436
    IG_FLMN; Filamin-type immunoglobulin domains
    COG5069
    Location:33 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

  7. XM_040646066.2 → XP_040502000.1  filamin-B isoform X2

    UniProtKB/TrEMBL
    A0A3Q2U9M2, F1N8D4
    Related
    ENSGALP00010039995.1, ENSGALT00010065729.1
    Conserved Domains (2) summary
    smart00557
    Location:1440 → 1533
    IG_FLMN; Filamin-type immunoglobulin domains
    COG5069
    Location:33 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    9061591..9140039
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925966.1 → XP_046781922.1  filamin-B isoform X10

    UniProtKB/TrEMBL
    F1N8D4

  2. XM_046925962.1 → XP_046781918.1  filamin-B isoform X7

    UniProtKB/TrEMBL
    F1N8D4

  3. XM_046925967.1 → XP_046781923.1  filamin-B isoform X11

    UniProtKB/TrEMBL
    F1N8D4

  4. XM_046925963.1 → XP_046781919.1  filamin-B isoform X8

    UniProtKB/TrEMBL
    F1N8D4

  5. XM_046925965.1 → XP_046781921.1  filamin-B isoform X9

    UniProtKB/TrEMBL
    F1N8D4

  6. XM_046925961.1 → XP_046781917.1  filamin-B isoform X6

    UniProtKB/TrEMBL
    F1N8D4

  7. XM_046925960.1 → XP_046781916.1  filamin-B isoform X6

    UniProtKB/TrEMBL
    F1N8D4

  8. XM_046925964.1 → XP_046781920.1  filamin-B isoform X3

    UniProtKB/TrEMBL
    A0A1D5NYG3, F1N8D4
Nucleotide Protein
Heading Accession and Version

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