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KIT KIT proto-oncogene, receptor tyrosine kinase [ Gallus gallus (chicken) ]

Gene ID: 378783, updated on 13-Apr-2026
Official Symbol
KITprovided by CGNC
Official Full Name
KIT proto-oncogene, receptor tyrosine kinaseprovided by CGNC
Primary source
CGNC:10414
See related
Ensembl:ENSGALG00010013314
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
SCFR
Annotation information
Annotation category: suggests misassembly
Orthologs
all
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See KIT in Genome Data Viewer
Location:
chromosome: 4
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (64787795..64839844, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (64770973..64822939, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 165 Neighboring gene steroid 5 alpha-reductase 3 Neighboring gene kinase insert domain receptor Neighboring gene uncharacterized LOC112532339 Neighboring gene uncharacterized LOC124417930 Neighboring gene platelet-derived growth factor receptor, alpha polypeptide

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The identification of c-Kit-positive cells in the intestine of chicken. Yang P, et al. Poult Sci, 2012 Sep. PMID 22912461
  2. Cloning and expression of the chicken c-kit proto-oncogene. Sasaki E, et al. Gene, 1993 Jun 30. PMID 7685729
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Fc receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Kit signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
mast/stem cell growth factor receptor Kit
Names
c-kit
proto-oncogene c-Kit
proto-oncogene tyrosine-protein kinase Kit
tyrosine-protein kinase Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NP_989692.1
XP_046771373.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204361.1 → NP_989692.1  mast/stem cell growth factor receptor Kit precursor

    See identical proteins and their annotated locations for NP_989692.1

    Status: PROVISIONAL

    Source sequence(s)
    D13225
    UniProtKB/Swiss-Prot
    Q08156
    Related
    ENSGALP00010018822.1, ENSGALT00010032032.1
    Conserved Domains (6) summary
    cd00096
    Location:122 → 184
    Ig; Immunoglobulin domain
    cd05860
    Location:297 → 397
    Ig4_SCFR; Fourth immunoglobulin (Ig)-like domain of stem cell factor receptor (SCFR)
    smart00410
    Location:213 → 292
    IG_like; Immunoglobulin like
    cd05104
    Location:539 → 913
    PTKc_Kit; Catalytic domain of the Protein Tyrosine Kinase, Kit
    pfam00047
    Location:205 → 291
    ig; Immunoglobulin domain
    pfam07714
    Location:575 → 909
    Pkinase_Tyr; Protein tyrosine kinase

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    64787795..64839844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    64770973..64822939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915417.1 → XP_046771373.1  mast/stem cell growth factor receptor Kit isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08156.1 GenPept UniProtKB/Swiss-Prot:Q08156

Gene LinkOut

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