Txlnb taxilin beta [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Txlnbprovided by MGI
Official Full Name: taxilin betaprovided by MGI
Primary source: MGI:MGI:2671945
See related: Ensembl:ENSMUSG00000039891 AllianceGenome:MGI:2671945
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mdp77; 2310001N14Rik
Summary: Predicted to enable syntaxin binding activity. Predicted to be located in cytoplasm. Is expressed in dorsal root ganglion; glossopharyngeal ganglion; medulla oblongata basal plate mantle layer; trigeminal ganglion; and ventral grey horn. Orthologous to human TXLNB (taxilin beta). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in heart adult (RPKM 41.1) and mammary gland adult (RPKM 4.0) See more
Orthologs: human all
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Genomic context

Location:: 10; 10 A2

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (17671967..17721411)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (17796219..17845663)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results demonstrate that beta-taxilin participates in myogenesis through suppressing the function of dysbindin to inhibit the differentiation of C2C12 myoblasts into myotubes.
Title: β-Taxilin participates in differentiation of C2C12 myoblasts into myotubes.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D10Mit50 (e-PCR), detects polymorphism
- UniSTS:126230

Homology

Homologs of the Txlnb gene: The Txlnb gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, and frog.
Orthologs from Annotation Pipeline: 460 organisms have orthologs with human gene Txlnb
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables syntaxin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: beta-taxilin

Names: muscle specific protein; muscle-derived protein 77

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.