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KLHL30 kelch like family member 30 [ Homo sapiens (human) ]

Gene ID: 377007, updated on 5-Aug-2022

Summary

Official Symbol
KLHL30provided by HGNC
Official Full Name
kelch like family member 30provided by HGNC
Primary source
HGNC:HGNC:24770
See related
Ensembl:ENSG00000168427 AllianceGenome:HGNC:24770
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in heart (RPKM 3.1), fat (RPKM 2.9) and 10 other tissues See more
Orthologs
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Genomic context

See KLHL30 in Genome Data Viewer
Location:
2q37.3
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (238138668..238152947)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (238628419..238642688)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (239047309..239061588)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene UBE2F-SCLY readthrough (NMD candidate) Neighboring gene selenocysteine lyase Neighboring gene Sharpr-MPRA regulatory region 4740 Neighboring gene espin like Neighboring gene erythroferrone Neighboring gene ILK associated serine/threonine phosphatase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ43374

General protein information

Preferred Names
kelch-like protein 30
Names
kelch-like 30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198582.4NP_940984.3  kelch-like protein 30

    See identical proteins and their annotated locations for NP_940984.3

    Status: VALIDATED

    Source sequence(s)
    AC016757, AK125364, BC103703, BC105696, BX280405
    Consensus CDS
    CCDS46555.2
    UniProtKB/Swiss-Prot
    Q0D2K2, Q6ZUS1
    Related
    ENSP00000386389.1, ENST00000409223.2
    Conserved Domains (6) summary
    smart00612
    Location:328377
    Kelch; Kelch domain
    PHA03098
    Location:29550
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:318363
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:23127
    BTB; BTB/POZ domain
    pfam01344
    Location:366407
    Kelch_1; Kelch motif
    pfam07707
    Location:135237
    BACK; BTB And C-terminal Kelch

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    238138668..238152947
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    238628419..238642688
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)