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RBM44 RNA binding motif protein 44 [ Homo sapiens (human) ]

Gene ID: 375316, updated on 4-Nov-2022

Summary

Official Symbol
RBM44provided by HGNC
Official Full Name
RNA binding motif protein 44provided by HGNC
Primary source
HGNC:HGNC:24756
See related
Ensembl:ENSG00000177483 AllianceGenome:HGNC:24756
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable protein homodimerization activity. Predicted to be located in cytoplasm and intercellular bridge. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 9.6) and bone marrow (RPKM 0.5) See more
Orthologs
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Genomic context

See RBM44 in Genome Data Viewer
Location:
2q37.3
Exon count:
18
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (237798779..237842805)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (238288780..238332805)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (238707422..238751448)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene LRR binding FLII interacting protein 1 Neighboring gene Sharpr-MPRA regulatory region 7631 Neighboring gene Sharpr-MPRA regulatory region 7730 Neighboring gene small nucleolar RNA SNORD55/SNORD39 Neighboring gene receptor activity modifying protein 1 Neighboring gene VISTA enhancer hs1968

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ40411

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in intercellular bridge ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080504.3NP_001073973.3  RNA-binding protein 44

    Status: VALIDATED

    Source sequence(s)
    AC012076
    Consensus CDS
    CCDS46554.2
    UniProtKB/Swiss-Prot
    A0AUW3
    Related
    ENSP00000321179.5, ENST00000316997.9
    Conserved Domains (1) summary
    cl17169
    Location:829904
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    237798779..237842805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017004055.2XP_016859544.1  RNA-binding protein 44 isoform X1

  2. XM_017004054.2XP_016859543.1  RNA-binding protein 44 isoform X1

  3. XM_005246075.2XP_005246132.1  RNA-binding protein 44 isoform X2

    See identical proteins and their annotated locations for XP_005246132.1

    Conserved Domains (1) summary
    cd12248
    Location:827900
    RRM_RBM44; RNA recognition motif in RNA-binding protein 44 (RBM44) and similar proteins
  4. XM_011511152.3XP_011509454.1  RNA-binding protein 44 isoform X3

  5. XM_017004057.2XP_016859546.1  RNA-binding protein 44 isoform X4

  6. XM_011511153.3XP_011509455.1  RNA-binding protein 44 isoform X5

  7. XM_017004056.2XP_016859545.1  RNA-binding protein 44 isoform X1

  8. XM_017004058.3XP_016859547.1  RNA-binding protein 44 isoform X6

  9. XM_011511155.2XP_011509457.1  RNA-binding protein 44 isoform X7

    See identical proteins and their annotated locations for XP_011509457.1

    UniProtKB/Swiss-Prot
    Q6ZP01
    Conserved Domains (1) summary
    cd12248
    Location:1487
    RRM_RBM44; RNA recognition motif in RNA-binding protein 44 (RBM44) and similar proteins

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    238288780..238332805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_198852.1: Suppressed sequence

    Description
    NM_198852.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.