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CATIP ciliogenesis associated TTC17 interacting protein [ Homo sapiens (human) ]

Gene ID: 375307, updated on 18-Aug-2020

Summary

Official Symbol
CATIPprovided by HGNC
Official Full Name
ciliogenesis associated TTC17 interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:25062
See related
Ensembl:ENSG00000158428
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C2orf62
Expression
Biased expression in testis (RPKM 1.8), kidney (RPKM 1.1) and 13 other tissues See more
Orthologs

Genomic context

See CATIP in Genome Data Viewer
Location:
2q35
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (218356757..218368393)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (219221579..219233003)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene PNKD metallo-beta-lactamase domain containing Neighboring gene CATIP antisense RNA 2 Neighboring gene microRNA 6810 Neighboring gene ribosomal protein L19 pseudogene 5 Neighboring gene CATIP antisense RNA 1 Neighboring gene solute carrier family 11 member 1 Neighboring gene CTD small phosphatase 1 Neighboring gene microRNA 26b

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC50811

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ciliogenesis-associated TTC17-interacting protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320865.2NP_001307794.1  ciliogenesis-associated TTC17-interacting protein isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC021016
    UniProtKB/Swiss-Prot
    Q7Z7H3
    Conserved Domains (1) summary
    cl02594
    Location:333362
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains
  2. NM_198559.2NP_940961.1  ciliogenesis-associated TTC17-interacting protein isoform 2

    See identical proteins and their annotated locations for NP_940961.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 5' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AC021016
    Consensus CDS
    CCDS2414.1
    UniProtKB/Swiss-Prot
    Q7Z7H3
    Related
    ENSP00000289388.3, ENST00000289388.4
    Conserved Domains (1) summary
    cl02594
    Location:322351
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    218356757..218368393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011511148.2XP_011509450.1  ciliogenesis-associated TTC17-interacting protein isoform X2

    Conserved Domains (1) summary
    cl02594
    Location:277306
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains
  2. XM_005246539.4XP_005246596.1  ciliogenesis-associated TTC17-interacting protein isoform X1

    Conserved Domains (1) summary
    cl02594
    Location:291320
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains
  3. XM_005246541.4XP_005246598.1  ciliogenesis-associated TTC17-interacting protein isoform X3

    Conserved Domains (1) summary
    cl02594
    Location:224253
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains
  4. XM_011511150.2XP_011509452.1  ciliogenesis-associated TTC17-interacting protein isoform X4

    See identical proteins and their annotated locations for XP_011509452.1

    Conserved Domains (1) summary
    cl02594
    Location:207236
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains
  5. XM_017004053.2XP_016859542.1  ciliogenesis-associated TTC17-interacting protein isoform X5

  6. XM_011511149.2XP_011509451.1  ciliogenesis-associated TTC17-interacting protein isoform X4

    See identical proteins and their annotated locations for XP_011509451.1

    Conserved Domains (1) summary
    cl02594
    Location:207236
    DD_R_PKA; Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains
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