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SFT2D2 SFT2 domain containing 2 [ Homo sapiens (human) ]

Gene ID: 375035, updated on 22-Sep-2022

Summary

Official Symbol
SFT2D2provided by HGNC
Official Full Name
SFT2 domain containing 2provided by HGNC
Primary source
HGNC:HGNC:25140
See related
Ensembl:ENSG00000213064 AllianceGenome:HGNC:25140
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UNQ512; dJ747L4.C1.2
Summary
Predicted to be involved in protein transport and vesicle-mediated transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 9.9), bone marrow (RPKM 8.2) and 25 other tissues See more
Orthologs
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Genomic context

See SFT2D2 in Genome Data Viewer
Location:
1q24.2
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (168226004..168253021)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (167577504..167604523)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (168195242..168222259)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit NDUFA4-like Neighboring gene CRISPRi-validated cis-regulatory element chr1.9777 Neighboring gene ankyrin repeat domain 36B pseudogene 1 Neighboring gene RNA, U6 small nuclear 1310, pseudogene Neighboring gene T-box transcription factor 19

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: TBX19

Homology

Clone Names

  • FLJ34085

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vesicle transport protein SFT2B
Names
SFT2 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199344.3NP_955376.1  vesicle transport protein SFT2B

    See identical proteins and their annotated locations for NP_955376.1

    Status: VALIDATED

    Source sequence(s)
    AK290325, AL009051, BC068098
    Consensus CDS
    CCDS1271.1
    UniProtKB/Swiss-Prot
    O95562, Q6UWR8
    Related
    ENSP00000271375.3, ENST00000271375.7
    Conserved Domains (1) summary
    pfam04178
    Location:45155
    Got1; Got1/Sft2-like family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    168226004..168253021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    167577504..167604523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)