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TMEM205 transmembrane protein 205 [ Homo sapiens (human) ]

Gene ID: 374882, updated on 4-Oct-2020

Summary

Official Symbol
TMEM205provided by HGNC
Official Full Name
transmembrane protein 205provided by HGNC
Primary source
HGNC:HGNC:29631
See related
Ensembl:ENSG00000105518 MIM:613771
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UNQ501
Expression
Ubiquitous expression in liver (RPKM 32.8), thyroid (RPKM 28.6) and 25 other tissues See more
Orthologs

Genomic context

See TMEM205 in Genome Data Viewer
Location:
19p13.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (11342512..11346459, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (11453452..11457065, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene tetraspanin 16 Neighboring gene uncharacterized HSPC102 Neighboring gene RAB3D, member RAS oncogene family Neighboring gene coiled-coil domain containing 159 Neighboring gene phospholipid phosphatase related 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC3205, MGC110858

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 205
Names
MBC3205

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145416.2NP_001138888.1  transmembrane protein 205

    See identical proteins and their annotated locations for NP_001138888.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an internal segment in the 5' UTR, as compared to variant 1.
    Source sequence(s)
    BC091472, BE889078
    Consensus CDS
    CCDS32909.1
    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000468733.1, ENST00000593256.6
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  2. NM_001321112.2NP_001308041.1  transmembrane protein 205

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an internal segment in the 5' UTR, as compared to variant 1.
    Source sequence(s)
    AC024575, BQ639667, CB994930
    Consensus CDS
    CCDS32909.1
    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000466495.1, ENST00000588560.5
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  3. NM_001321113.2NP_001308042.1  transmembrane protein 205

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an internal segment in the 5' UTR, as compared to variant 1.
    Source sequence(s)
    AC024575, BM352837, CB994930
    Consensus CDS
    CCDS32909.1
    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000466986.1, ENST00000586590.5
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  4. NM_001321114.2NP_001308043.1  transmembrane protein 205

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an internal segment in the 5' UTR, as compared to variant 1.
    Source sequence(s)
    BM451378, CB994930
    Consensus CDS
    CCDS32909.1
    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000465553.1, ENST00000589555.5
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  5. NM_033408.4NP_212133.1  transmembrane protein 205

    See identical proteins and their annotated locations for NP_212133.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal segment in the 5' UTR, as compared to variant 1.
    Source sequence(s)
    BC008365, BE889078
    Consensus CDS
    CCDS32909.1
    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000398258.1, ENST00000447337.5
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  6. NM_198536.3NP_940938.1  transmembrane protein 205

    See identical proteins and their annotated locations for NP_940938.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longest transcript. Variants 1, 2, 3, 4, 5 and 6 encode the same protein.
    Source sequence(s)
    BC064948, BC091472, BE889078
    Consensus CDS
    CCDS32909.1
    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000346954.4, ENST00000354882.10
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    11342512..11346459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026769.1XP_016882258.1  transmembrane protein 205 isoform X1

  2. XM_024451500.1XP_024307268.1  transmembrane protein 205 isoform X2

    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  3. XM_024451501.1XP_024307269.1  transmembrane protein 205 isoform X2

    Related
    ENSP00000465149.1, ENST00000587948.5
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
  4. XM_005259899.2XP_005259956.1  transmembrane protein 205 isoform X2

    See identical proteins and their annotated locations for XP_005259956.1

    UniProtKB/Swiss-Prot
    Q6UW68
    UniProtKB/TrEMBL
    A0A024R7D3
    Related
    ENSP00000465483.1, ENST00000586956.5
    Conserved Domains (1) summary
    pfam13664
    Location:17114
    DUF4149; Domain of unknown function (DUF4149)
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